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Informationen zum Autor Lester Packer, Helmut Sies, Manfred Eggersdorfer, Enrique Cadenas Klappentext Under the direction of leading experts in oxidative stress! this book addresses cutting-edge areas of research regarding micronutrients and the brain: It discusses identification of brain-specific micronutrients that support function and molecular mechanisms underlying neuroprotectant activity. The book covers age-related metabolic pathways! mitochondrial nutrients! and neurodegeneration. Additional chapters cover flavonoids! cell signaling! and neuronal functions! as well as the role of choline! amino acids! metals! and other micronutrients in brain health and function. The text places a particular emphasis on lipoic acid! which is shown to be a therapeutic agent in neuropathologies. Zusammenfassung Addresses research related to processes of oxidative stress that affect brain function. This book identifies brain-specific micronutrients that support function as well as the molecular mechanisms underlying their neuroprotectant activity. It explores how brain micronutrients are found to be both metabolic and redox regulators. Inhaltsverzeichnis Neuroprotection after Cardiac Arrest by Avoiding Acute Hyperoxia and by Antioxidant Genomic Postconditioning. The Neuroprotective Role of Micronutrients in Parkinson’s. Food Antioxidants and Alzheimer’s Disease. Micronutrient Antioxidants, Cognition, and Neuropathology: A Longitudinal Study in the Canine Model of Human Aging. Excitatory Amino Acids, S-nitrosylation, and Protein Misfolding in Neurodegenerative Disease: Protection by Memantine and NitroMemantine at NMDA-Gated Channels. Cognitive and Behavioral Consequences of Iron Deficiency in Women of Reproductive Age. Micronutrient Needs of the Developing Brain: Priorities and Assessment. Therapeutics of Alzheimer’s Disease Based on Metal Bioavailability. Lipoic Acid as a Novel Treatment for Mild Cognitive Impairment and Early-Stage Alzheimer’s Disease. Zinc and the Cytoskeleton in Neuronal Signaling. Tocotrienol Neuroprotection: The Most Potent Biological Function of All Natural Forms of Vitamin E. Fruits, Nuts, and Brain Aging: Nutritional Interventions Targeting Age-Related Neuronal and Behavioral Deficits. Modulation of Multiple Pathways Involved in the Maintenance of Neuronal Function. Dietary Flavonoids as Neuroprotective Agents. Actions of Bioactive Phytochemicals in Cell Function and Alzheimer’s Disease Pathology. Does Ginkgo biloba Extract Exert an Effect on Alzheimer’s Disease Progression. Green Tea Polyphenols Protect Neurons against Alzheimer’s Disease and Parkinson’s Disease. Transport of Flavonoids into the Brain. Prevention and Treatment of Neurodegenerative Diseases by Spice-Derived Phytochemicals. Neurohormetic Properties of the Phytochemical Resveratrol. Sirtuin and Resveratrol. Acetyl-l-Carnitine and Ferulic Acid Action in Aging and Neurodegenerative Diseases. Evidence Required for Causal Inferences about Effects of Micronutrient Deficiencies during Development on Brain Health: DHA, Choline, Iron, and Vitamin D. Omega-3 Fatty Acids and Brain Function in Older People. Iron and Monoamine Oxidase in Brain Function and Dysfunction: Development of Neuroprotective-Neurorescue Drugs. Antioxidative Defense of Brain Microglial Cells. Branched-Chain Amino Acids and Brain Metabolism. ...
