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As a group, rickettsiae, and related bacteria, contain a number of human pathogens that have recently named as causes of `emerging diseases'. This unique volume offers a thorough and current review of information on the pathogenesis and immune response elicited by memebers of the genera Rickettsia, Ehrlichia, Coxiella, Orlentia, and Bartonella, in contributions authored by the expert clinicians and researchers who work with these organisms.
List of contents
Molecular Rickettsiology.- Immunity to Rickettsiae (Redux).- Cytokines Influencing Infections by Rickettsia Species.- Global Genetic Diversity of Spotted Fever Group Rickettsiae.- Surface Components of the Spotted Fever Group Rickettsiae.- Oxidative Cell Injury and Spotted Fever Group Rickettsiae.- Intracellular Development of Coxiella burnetii.- The Identification of Virulence Factors of Coxiella burnetti.- Human Granulocytic Ehrlichiosis.- The Immune Response to Ehrlichia chaffeensis.- Clinical Aspects of Bartonella Infections.- Virulence Determinants of Bartonella bacilliformis.- Stimulation of Angiogenesis and Protection from Oxidant Damage.
Summary
Offers a review of information on the pathogenesis and immune response elicited by members of the genera Rickettsia, Ehrlichia, Coxiella, Orlentia, and Bartonella, in contributions authored by the clinicians and researchers who work with these organisms.
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`Excellent...this text will prove valuable to current researchers, investigators interested in moving into this area and other immunologists and pathogenesis specialists needing a comparative perspective.'
Trends in Microbiology, August 1998
