Handbook of Drug Screening

Informationen zum Autor Ramakrishna Seethala, Litao Zhang Zusammenfassung Building upon the foundation of basics discussed in the previous edition, the Second Edition provides a more in-depth look at the latest methods and technologies of advanced drug screening, an essential function of drug discovery. Inhaltsverzeichnis Trends in Drug Discovery. Screening Strategies and Infrastructure in Drug Discovery. Logistics in Progression of Compounds to Clinical Development. Assay Technologies in Drug Screening. Proteomics Technologies in Drug Discovery. GPCR Screens. Nuclear Hormone Receptor Screens. Emerging Novel HTS Technologies for Cell Based Assays. In vitro Strategies for Ion Channel Screening in Drug Discovery. Wheat from Chaff: General and Mechanistic Triage of Screening Hits for Enzyme Targets. Protein Kinases and Phosphatases. MicroRNA Strategies in Drug Discovery. Strategies for Screening Biological in Drug Discovery. Cryopreserved Cells in Functional Cell-Based HTS Assays. High Content Screening Assay development. ADME-TOX, PK and Drug Metabolism in Drug Discovery. Compound Management for Drug Screening. Practical Approach to Quantitative High-Throughput Screening. Enabling the Large Scale Analysis of Quantitative High Throughput Screening Data. Nanotechnology in Drug Discovery.

Product details

• Authors: Seethala Ramakrishna, Ramakrishna (Bristol-Meyers Squibb Compa Seethala, Ramakrishna Zhang Seethala, SEETHALA RAMAKRISHNA ZHANG LITAO
• Assisted by: Seethala Ramakrishna (Editor), Ramakrishna Seethala (Editor), Litao Zhang (Editor), Zhang Litao (Editor)
• Publisher: Taylor & Francis Ltd.
• Languages: English
• Product format: Hardback
• Released: 24.06.2009
• EAN: 9781420061680
• ISBN: 978-1-4200-6168-0
• No. of pages: 504
• Series: Drugs and the Pharmaceutical Sciences; Drugs and the Pharmaceutical Sciences
• Subjects: Natural sciences, medicine, IT, technology > Medicine > General; Medical research, MEDICAL / Pharmacy, SCIENCE / Chemistry / General, MEDICAL / Pharmacology, Biology, life sciences, Pharmaceutical technology, Pharmaceutical chemistry and technology