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This volume attempts to demonstrate that increasingly sophisticated diagnostic and staging approaches are helping to move chemotherapy and radiotherapy into the preoperative neoadjuvant setting. This fundamental alteration is based on the awareness that even early-stage solid tumor disease is frequently systemic at the time of presentation, at least on a subclinical level. Although the primary tumor may be controllable by surgery with radiotherapy, the uncontrolled distant disease ultimately determines patient survival.
The other perspective driving the neoadjuvant approach is an emerging awareness that, for most solid tumor systems, neoadjuvant treatment responses can facilitate less mutilating surgery with comparable levels of local disease control. These unifying concepts have reached increasing acceptance and are being extended via the crucible of clinical trials.
Surgical Oncology seeks to impart a sense of what is pertinent in the rapidly evolving field of surgical oncology. By identifying new developments in each solid tumour site, the reader will gain an anticipatory sense of where the discipline of surgical oncology is headed.
List of contents
1. Prospective Randomized Trials in Melanoma: Defining Contemporary Surgical Roles; M.I. Ross. 2. Advances in Rectal Cancer Treatment; J.M. Skibber. 3. Molecular and Surgical Advances in Pediatric Tumors; C.A. Corpron, et al. 4. Advances in Reconstructive for Cancer Patients; M.A. Schusterman, et al. 5. New Developments in Soft Tissue Sarcoma; P.W.T. Pisters, et al. 6. Advances in the Diagnosis and Treatment of Adenocarcinoma of the Pancreas; D.B. Evans, et al. 7. Recent Advances in Bone Sarcomas; A.W. Yasko, M.E. Johnson. 8. Thyroid Carcinoma; A.M. Gillenwater, R.S. Weber. 9. Changing Trends in the Diagnosis and Treatment of Early Breast Cancer; K.K. Hunt, M.I. Ross. 10. Classification, Staging, and Management of Non-Hodgkin's Lymphomas; P.F. Mansfield, et al. 11. Multiple Endocrine Neoplasia; J.A. Miller, J.A. Norton. 12. Advances in the Diagnosis and Treatment of Gastrointestinal Neuroendocrine Tumors; J.E. Lee, D.B. Evans. 13. Contemporary Approaches to Gastric Carcinoma; B. Cady. 14. New Strategies in Locally Advanced Breast Cancer; S.E. Singletary, et al. 15. Biliary Tract Cancer; S.A. Curley. 16. Minimally Invasive Surgery in Surgical Oncology; J.W. Milsom, et al. 17. Prognostic Factors in Surgical Resection for Hepatocellular Carcinoma; B.J. Roseman, M.S. Roh. 18. Colon Cancer; D.M. Ota.
Summary
The other perspec tive driving the neoadjuvant approach is an emerging awareness that for most solid tumor systems, neoadjuvant treatment responses can facilitate less muti lating surgery with comparable levels of local disease control.
