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Cholestatic disorders of infancy and adulthood represent a major group of causes of end-stage chronic liver disease. There has been great scientific interest in these disorders in recent years, so the time has come to evaluate treatment modalities in old and even new cholestatic diseases. Since secondary malnutrition plays an important role in inducing multiorgan morbidity in these patients, nutritional and metabolic aspects need better understanding. The influence of disease and nutrition-related problems on liver transplantation as the ultimate therapy of cholestatic disorders is also of current interest.
This book, the proceedings of an International Falk Workshop held in Hamburg, Germany, 25-26 January 1996, brings together a group of experts from around the world to explore and elucidate these topics. It will be of interest to all hepatologists and clinicians, especially paediatricians.
List of contents
Preface. Section I: Treatment Modalities in PBC. 1. Primary Biliary Cirrhosis (PBC) - A Suitable Case for Steroid Treatment? O.F.W. James. Section II: Old and New Cholestatic Diseases on Infancy and Childhood. 2. Finding Your Way in Cholestatic Paediatric Liver Disease During Infancy; K. Pittschieler. 3. Progressive Familial Intrahepatic Cholestasis; E.M. Alonso, et al. 4. Clinical Relevance of Familial Cholestatic Disorders in Infancy and Childhood; M. Burdelski. Section III: Nutritional Aspects in Cholestatic Disease. 5. Nutrients, Cell Volume and Bile Secretion; M. Wettstein, et al. 6. Nutritional Aspects of Cholestatic Liver Disease in Children; D. Drews. 7. Effects of Cholestasis on Lipid Metabolism; S. Jäckle, U. Beisiegel. 8. Cholestasis and the Bone; U. Beuers, G.-A. Kullak-Ublick. Section IV: Transplantation in Cholestatic Disease. 9. Primary Biliary Cirrhosis: When to Transplant; R.H. Wiesner. 10. Diagnosis and Endoscopic Follow-up of Primary Sclerosing Cholangitis Patients; S. Wagner, et al. 11. Recurrence of Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis After Liver Transplantation; J. Neuberger. Index.
Summary
Cholestatic disorders of infancy and adulthood represent a major group of causes of end-stage chronic liver disease. There has been great scientific interest in these disorders in recent years, so the time has come to evaluate treatment modalities in old and even new cholestatic diseases.
