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Informationen zum Autor Edited by: Vijeya Ganesan , Institute of Child Health, University College London Fenella Kirkham , Institute of Child Health, University College London and Great Ormond Street Hospital, London Klappentext The field of stroke and cerebrovascular disease in children is one in which there has been much recent research activity, leading to new clinical perspectives.This book for the first time summarizes the state of the art in this field. A team of eminent clinicians, neurologists and researchers provide an up-to-the-minute account of all aspects of stroke and cerebrovascular disease in children, ranging from a historical perspective to future directions, through epidemiology, the latest neuroimaging techniques, neurodevelopment, comorbidities, diagnosis and treatment. The authors’ practical approach to the clinical problems makes this essential reading for practising clinicians. It will also be of interest to researchers in the field. Zusammenfassung This book gives a broad-ranging account of the current findings and a practical approach to the clinical problems. Inhaltsverzeichnis AUTHORS' APPOINTMENTS ix 1. CHILDHOOD STROKE - THE UNKINDEST CUT OF ALL: A HISTORY OF CEREBROVASCULAR DISEASE IN CHILDHOOD 1 Andrew N. Williams and Fenella J. Kirkham 2. DEVELOPMENT OF THE BRAIN CIRCULATION 17 Chao Bao Luo, Marina Sachet Ferreira, Hortensia Alvarez, Georges Rodesch and Pierre L. Lasjaunias 3. THE EPIDEMIOLOGY OF CHILDHOOD STROKE 22 Gabrielle deVeber 4. CLINICAL AND IMAGING FEATURES OF CHILDHOOD STROKE 27 4.1 CLINICAL SYNDROMES 27 4.1.1 ANTERIOR CIRCULATION STROKE 27 Fenella J. Kirkham 4.1.2 POSTERIOR CIRCULATION STROKES IN CHILDREN 38 Bhuwan P. Garg 4.1.3 SPINAL CORD STROKE 43 Bettina Harms, Jason MacDonald and Fenella J. Kirkham 4.2 NEUROIMAGING 48 4.2.1 IMAGING OF PAEDIATRIC STROKE 48 Dawn E. Saunders and W.K. Kling Chong 4.2.2 RECENT ADVANCES IN MAGNETIC RESONANCE IMAGING 57 Fernando Calamante, Jacques-Donald Tournier and Alan Connelly 5. RISK FACTORS AND TRIGGERS FOR CRYPTOGENIC (AND SYMPTOMATIC) STROKE 84 5.1 CEREBROVASCULAR DISEASES FROM INFECTIOUS/INFLAMMATORY ORIGIN 84 Guillaume Sébire and Benedict Michel (with a section on human immunodeficiency virus by Nomazulu Dlamini and Fenella J. Kirkham) 5.2 THROMBOPHILIA AND CHILDHOOD STROKE 91 Ulrike Nowak-Göttl and Ronald Sträter 5.3 HYPERTENSION AND CHILDHOOD STROKE 94 Juan C. Kupferman, Fenella J. Kirkham and Steven Pavlakis 5.4 TRAUMA 96 Fenella J. Kirkham 5.5 IRON DEFICIENCY 96 Fenella J. Kirkham 5.6 PATENT FORAMEN OVALE AND PARADOXICAL EMBOLISM 96 Vijeya Ganesan and Fenella J. Kirkham 6. ARTERIAL ISCHAEMIC STROKE AND VASCULAR DISEASE IN CHILDHOOD 107 6.1 CERVICOCEPHALIC ARTERIAL DISSECTIONS IN CHILDHOOD AND ADOLESCENCE 107 Göran Darius Hildebrand and Stéphane Chabrier 6.2 TRANSIENT CEREBRAL ARTERIOPATHY 115 Guillaume Sébire 6.3 MOYAMOYA SYNDROME IN CHILDHOOD 120 Vijeya Ganesan and Brian G.R. Neville 6.4 CEREBRAL VASCULITIS 127 Russell C. Dale 6.5 VASOSPASM 131 Fenella J. Kirkham 6.6 TORTUOSITY AND DOLICHOECTASIA 132 Katharine M.L. Forrest 6.7 DEVELOPMENTAL VENOUS ANOMALIES 133 Mara Prengler and Fenella J. Kirkham 7. CEREBAL SINOVENOUS (VENOUS SINUS) THROMBOSIS 145 Gabrielle deVeber 8. HAEMORRHAGIC STROKE 160 8.1 NON-TRAUMATIC INTRACRANIAL HAEMORRHAGE IN CHILDREN 160 Vijeya Ganesan and Dawn E. Saunders 8.2 SURGICAL TREATMENT OF HAEMORRHAGIC STROKE IN CHILDREN 169 Joan P. Grieve and Neil D. Kitchen