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Informationen zum Autor Mone Zaidi is the editor of Skeletal Biology and Medicine, Part A: Aspects of Bone Morphogenesis and Remodeling, published by Wiley. Klappentext This volume highlights new insights into the mechanisms of bone development, including cellular and mechanical factors, receptors, and signaling pathways and their role in both normative and pathologic states of bone. The first of two volumes, the volume comprises three sections: (1) insights into skeletal development, including, among others, novel ideas about the role of the perichondrium in skeletogenesis, current studies on joint formation, and the human consequences of dysregulated morphogenic signaling; (2) a traditional series of papers, both reviews and original research articles on bone cells--osteoblasts, osteoclasts, and osteocytes--in relation to mechanisms underlying their formation, fate, and function; and (3) new information on the role of hormones, both steroids and peptides, as well as cytokines and the central nervous system in regulating skeletal remodeling. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member. Zusammenfassung * Part of the Annals of the New York Academy of Sciences series. *Annals volumes are available for sale as individual books or as a journal. For more information on subscriptions! please visit www. blackwellpublishing. com/nyas. . Inhaltsverzeichnis The 2nd Conference on Skeletal Medicine and Biology: Overview and Comments: Mone Zaidi. Intracellular Protein Degradation: From a Vague Idea Through the Lysosome and the Ubiquitin-Proteasome System and onto Human Diseases and Drug Targeting: Aaron Ciechanover. Part I: New Insights into Bone Development:. 1. Multiplicity of BMP Signaling in Skeletal Development: Xiangwei Wu , Weibin Shi , Xu Cao. 2. Nephroblastoma Overexpressed (NOV) Is A Novel Bone Morphogenetic Protein Antagonist: Ernesto Canalis. 3. The Role of the Perichondrium in Fetal Bone Development: Henry M. Kronenberg. 4. The PTHrP Functional Domain Is at the Gates of Endochondral Bones: Arthur E. Broadus, Carolyn Macica, Xuesong Chen. 5. Axin1 and Axin2 Are Regulated by TGF-ß and Mediate Crosstalk between TGF-ß and Wnt SignalingPathways: Debbie Y. Dao, Xue Yang, Di Chen, Michael Zuscik, and Regis J. O'Keefe,. 6. Synovial Joint Formation during Mouse Limb Skeletogenesis: Roles of Indian Hedgehog Signaling: Eiki Koyama, Takanaga Ochiai, Ryan B. Rountree, Motomi Enomoto-Iwamoto, Masahiro Iwamoto, and Maurizio Pacifici. 7. Morphogen Receptor Genes and Metamorphogenes: Skeleton Keys to the Metamorphosis: Frederick S. Kaplan, Jay Groppe, Robert J. Pignolo, and Eileen M. Shore. 8. Differential Effects of IVEGF on Joint Formation During Liimb Development: Gloria Emelí Cortina-Ramírez and Jesús Chimal-Monroy. 9. Negative Regulation of Otic Capsule Chondrogenesis: It Can Make You Smad: Wei Liu, Sydney Butts, Harold Kim, Dorothy A. Frenz. 10. A Novel Transgenic Mouse Model to Study the Osteoblast lineage in vivo: Christa Maes, Tatsuya Kobayashi, Henry M. Kronenberg. Part II: Formation, Function and Fate of Bone Cells:. 11. Balanced Regulation of Proliferation, Growth, Differentiation, and Degradation In Skeletal Cells: Harry C Blair, Li Sun, Ronald A Kohanski. 12. Control of Postnatal Bone Mass by the Zinc Finger Adapter Protein Schnurri-3: Laurie H. Glimcher , Dallas C. Jones,...
