Practical Lipid Management - Concepts and Controversies

Informationen zum Autor Peter P. Toth , M.D., Ph.D., FAAFP, FICA, FAHA, FACC. Director of Preventive Cardiology, Sterling Rock Falls Clinic, Ltd., Illinois, USA; Chief of Medicine, CGH Medical Center, Illinois, USA; Visiting Clinical Associate Professor, University of Illinois School of Medicine, USA; Editor-in-Chief, Journal of Applied Research?in Clinical and Experimental Therapeutics . Kevin C. Maki, PhD. President, Provident Clinical Research & Consulting, Inc., USA. Klappentext A practical text on the clinical management of dyslipidemias, Practical Lipid Management balances conceptual development and pathophysiology with a straightforward approach to the identification and treatment of abnormalities in lipid metabolism.The book explores the role of novel risk markers in clinical practice, summarizes the current guidelines for lipid management, and offers a critical and systematic approach to interpreting the results of clinical trials. A feature of the book is a set of sidebars which explore current controversies and unanswered questions in clinical lipidology. The treatment of specific dyslipidemias is illustrated with case studies. Treatment algorithms are also provided.Practical Lipid Management* details the relationship between specific lipids, lipoproteins and cardiovascular disease* provides guidance on the etiology and diagnosis of lipid abnormalities* summarizes current understanding of atherogenesis* reviews the evidence base for the use of therapeutic lifestyle change and specific lipid-lowering medications to reduce morbidity and mortality from cardiovascular disease* includes a cutting edge discussion of the controversies arising from the results of the ENHANCE (Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression) TrialPractical Lipid Management provides a concise summary of best practice according to various international guidelines, making it a useful tool for all primary care physicians and others involved in the management of diseases such as diabetes, cardiovascular disease and stroke. It will serve as an evidence-based, rapid, and valuable resource for family physicians, internists, nurse practitioners, physician assistants, cardiologists, endocrinologists and allied health professionals involved in the care of patients with lipid disorders. Zusammenfassung Provides a concise, user-friendly overview of lipid management Forms a useful tool for all primary care physicians and others involved in the management of dyslpidaemias and diseases such as diabetes and atherothrombosis Features a summary of the international guidelines and addresses current controversies in the treatment of lipid disorders. Inhaltsverzeichnis Foreword. Preface. Acknowledgements. Chapter 1 Epidemiology of Lipids, Lipid Management and Risk for Coronary Heart Disease: An Overview. 1.1 Early History of Cardiovascular Epidemiology. 1.2 Lipid Risk Factors are Central to Efforts at CHD Prevention. 1.3 LDL-C and CHD Risk. 1.4 LDL-C Lowering and CHD Risk Reduction. 1.5 Other Atherogenic Lipoproteins: Atherogenic Remnants. 1.6 HDL-C and CHD Risk. 1.7 Trends in Lipids and Lipid Management in the USA. 1.8 The National Cholesterol Education Program Evaluation Project Using Novel E-Technology (NEPTUNE) II Survey. Controversy: Should a Measure of Atherogenic Lipoprotein Particle Number be used in Risk Assessment And/Or to Evaluate the Response to Lipid Therapy? Chapter 2 Vascular Biology and Atherogenesis. 2.1 Introduction. 2.2 Arterial Structure. 2.3 Endothelial Cell Function and Dysfunction. 2.4 The Role of Monocytes and Lymphocytes. 2.5 Atheromatous Plaques...

List of contents

Foreword.
 
Preface.
 
Acknowledgements.
 
Chapter 1 Epidemiology of Lipids, Lipid Management and Risk for Coronary Heart Disease: An Overview.
 
Controversy: Should a Measure of Atherogenic Lipoprotein Particle Number be used in Risk Assessment And/Or to Evaluate the Response to Lipid Therapy?
 
Chapter 2 Vascular Biology and Atherogenesis.
 
Chapter 3 Detection, Evaluation, and Treatment Goals for Lipid Disorders in Adults.
 
Controversy: Should Treatment Guidelines Include Targets for the Total/HDL Cholesterol Ratio?
 
Chapter 4 Therapeutic Lifestyle Changes in the Management of Lipid Disorders and the Metabolic Syndrome.
 
Chapter 5 Management of Elevated Low-Density Lipoprotein Cholesterol.
 
Controversy: How Low Should We Go?
 
Controversy: Risks and Benefits of High-Dose Statin Therapy Versus Combination Lipid Drug Therapy.
 
Controversy: Do the Benefits of Low-Density Lipoprotein Cholesterol Reduction Depend Strictly on "How Low You Go" or also on "How You Get There"?
 
Chapter 6 Management of Elevated Triglycerides and Non-High-Density Lipoprotein Cholesterol.
 
Controversy: Do we Need a Triglyceride Treatment Target to Insure a Predominance of Larger, More Buoyant LDLParticles?
 
Chapter 7 Management of Depressed High-Density Lipoprotein Cholesterol.
 
Controversy: Do we Need HDL Treatment Goals?
 
Chapter 8 Lipid Management in Population Subsets: Women, the Elderly, Ethnic Minorities, Children, and Adolescents.
 
Chapter 9 Emerging Risk Factors and Biomarkers of Cardiovascular Disease.
 
Chapter 10 A Primer on Clinical Trials and Critical Review of Clinical Trial Reports for the Clinician.
 
Chapter 11 Case Studies.
 
Index.

Report

"This is an essential book for physicians who manage patients with lipid disorders. There is no comparable book that provides the depth of information this one does while remaining practical in approach." ( Doody s , September 2009)

Product details

• Authors: Kevin Maki, Kevin (Provident Clinical Research & Consulting Maki, Kevin C. Maki, Peter Toth, Peter P Toth, Peter P. Toth, Peter P. (Sterling Rock Falls Clinic Toth, Peter P. Maki Toth, Pp Toth, Toth Peter P.
• Publisher: Wiley, John and Sons Ltd
• Languages: English
• Product format: Hardback
• Released: 10.10.2008
• EAN: 9780470056905
• ISBN: 978-0-470-05690-5
• No. of pages: 252
• Subjects: Guides; Natural sciences, medicine, IT, technology > Medicine; Neurologie, Medizin, Geriatrie, Endokrinologie, Neurology, KARDIOVASKULÄRE ERKRANKUNGEN, Endocrinology, Geriatric medicine, Medical Science, Cardiovascular Disease