Antibodies in Viral Infection

Antibodies are central to vaccines and it is becoming increasingly apparent that understanding how antibodies combat viruses could be crucial in a new era of vaccine development. This book describes the state of the art in explaining the anti-viral activity of antibodies at the molecular level, with chapters from many of the leaders in the field.

List of contents

List of Contents.- Antibody Interactions with Rhinovirus: Lessons for Mechanisms of Neutralizationand the Role of Immunity in Viral Evolution.- Structural Studies on Antibody Interacting with Viruses.- Shape and Electrostatic Complementarity at Viral Antigen-Antibody Complexes.- Structural Studies on Viral Escape from Antibody Neutralization.- Affinity, Complementarity, Cooperativity, and Specificity in Antibody Recognition.- Mechanisms of Virus Neutralization by Antibody.- A Model for Neutralization of Viruses Based on Antibody Coating of the Virion Surface.- Antibody-Mediated Enhancement of Viral Disease.- The Role of the Antibody Response in Influenza Virus Infection.- Role of Antibodies in Controlling Alphavirus Infection of Neurons.- Role of Mucosal Antibodies in Viral Infections.- The Role of the Complement System in Virus Infections.- Intrabodies as Antiviral Agents.- T-Bodies as Antiviral Agents.

Summary

Antibodies are central to vaccines and it is becoming increasingly apparent that understanding how antibodies combat viruses could be crucial in a new era of vaccine development. This book describes the state of the art in explaining the anti-viral activity of antibodies at the molecular level, with chapters from many of the leaders in the field.

Product details

• Authors: D. R. Burton
• Assisted by: Dennis R. Burton (Editor), Denni R Burton (Editor), Dennis R Burton (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Hardback
• Released: 19.02.2009
• EAN: 9783540416111
• ISBN: 978-3-540-41611-1
• No. of pages: 309
• Weight: 635 g
• Illustrations: IX, 309 p. 51 illus., 12 illus. in color.
• Series: Current Topics in Microbiology and Immunology; Current Topics in Microbiology and Immunology
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine; B, Immunology, Mikrobiologie (nicht-medizinisch), Medical microbiology & virology, Biomedical and Life Sciences, Virology, virus infection, viral disease