Case Studies in Ethics and HIV Research

This book represents the compilation of efforts by researchers across the country, each of whom is dedicated not only to the prevention and elimination of HIV infection, but also to the conduct of research according to the highest ethical pr- ciples. The authors of the case studies have graciously agreed to share their ex- riences in conducting research, which raised questions for them and will motivate us to further inquiry and examination. The views that are presented in this text are diverse and readers may or may not agree with the analyses of the editor-authors or the authors of the case studies. We do not aim for agreement among readers, but rather, the studied analysis of the ethical issues raised in the conduct of HIV research. We clearly emphasize the protection of the individuals participating in such research, as well as their communities, and view research not as an enterprise undertaken by researchers, but rather as a negotiated exchange between researchers, participants, and c- munities that also involves interplay with funding sources, ancillary partners, and governments.

List of contents

Human Rights, International Guidelines, and HIV Research.- U.S. Regulations and HIV-Related Research.- The Informed Consent Process.- Working with Boards and Committees: ECs, DSMBs, CABs.- Researcher-Participant Relations.- Researcher-Community Relations.- Recruiting for HIV-Related Research.- Clinical Trials.- Observational Studies.- Behavioral Intervention Studies.- Ethical Issues in Multicenter/Multisite Studies.- HIV Research with Children.- HIV-Related Research with Cognitively Impaired Persons.- Studies with Minority Populations.- Research in International Settings.- Activity-Defined Populations.- Training the Next Generation of Researchers.- Training Community.

About the author

Dr. Loue is known internationally for HIV research with minority communities, as well as research ethics and epidemiology. Dr. Loue has written books focusing on Epidemiology, Disease Prevention, and Sexual Practices.
Earl Pike has been engaged in community-based HIV service and prevention program provision and management for over 20 years, and directs Ohio's largest HIV/AIDS service, education, and advocacy.

Summary

This important work takes as its subject one of medicine’s most pressing arenas of ethical debate. There has been a consistent interest in ethical issues arising in the context of HIV research. Ongoing international and multi-site studies and the continuing search for an HIV vaccine continue to prompt examination of how this research is conducted. Also examined are how participants are engaged in the studies and the obligations of the researchers to individual participants and their communities during the course of and following the conclusion of the research. Each chapter of this book is authored primarily by one of the editors (secondarily by the other) and is accompanied by case studies. Each case study has been authored by an HIV/AIDS researcher with experience in the subject matter of the chapter. The case studies focus on an actual ethical dilemma encountered by the researcher, with suggestions on how it can be resolved. Each chapter addresses relevant issues and emphasizes particular ethical principles.

Additional text

From the reviews:
"The use of case studies makes this a rich book that contributes to the research ethics literature. The discussion of the cases and the ethical issues each case raises give readers a better appreciation of the breadth and depth of the relevant ethical and scientific concerns."  -Ana Smith Iltis, Ph.D., St. Louis University Center for Health Care Ethics, DOODY REVIEW                                                             
"Loue (Case Western Reserve Univ.) and Pike (AIDS Taskforce of Greater Cleveland) present a series of reflections surrounding HIV/AIDS research. … The chapter topics and case studies are apt, and the analyses throughout are thought-provoking. The volume is well suited for use by science and medical students. … Summing Up: Recommended. Upper-division undergraduates through professionals/practitioners." -R. E. Kraft, CHOICE, Vol. 45 (7), 2008
"I am not sure who would want to read a more comprehensive treatment of the subject than this work. ... Never was a treatise on research ethics more needed." -Philip E. Veenhuis, MD, MPH. JAMA. Vol. 300(5), 2008
"For the first time, scholars tackle the moral complexities of the work in which HIV researchers have been engaged and highlight implications of the decisions being made in the field. These are decisions that can literally have life and death implications for those who participate in HIV-related research. ... Loue and Pike have found a way to establish a united approach, addressing these issues through highlighting their commonly held beliefs and perspectives, and producing a beautifullyorchestrated volume where the realities of science dance in perfect tempo with the needs for protecting human rights.  ... important reading for numerous audiences ..." -Julianne M. Serovich, Ph.D., Columbus, Ohio. The Journal of Legal Medicine, 29 (2), 2008

Report

From the reviews:
"The use of case studies makes this a rich book that contributes to the research ethics literature. The discussion of the cases and the ethical issues each case raises give readers a better appreciation of the breadth and depth of the relevant ethical and scientific concerns."  -Ana Smith Iltis, Ph.D., St. Louis University Center for Health Care Ethics, DOODY REVIEW                                                             
"Loue (Case Western Reserve Univ.) and Pike (AIDS Taskforce of Greater Cleveland) present a series of reflections surrounding HIV/AIDS research. ... The chapter topics and case studies are apt, and the analyses throughout are thought-provoking. The volume is well suited for use by science and medical students. ... Summing Up: Recommended. Upper-division undergraduates through professionals/practitioners." -R. E. Kraft, CHOICE, Vol. 45 (7), 2008
"I am not sure who would want to read a more comprehensive treatment of the subject than this work. ... Never was a treatise on research ethics more needed." -Philip E. Veenhuis, MD, MPH. JAMA. Vol. 300(5), 2008
"For the first time, scholars tackle the moral complexities of the work in which HIV researchers have been engaged and highlight implications of the decisions being made in the field. These are decisions that can literally have life and death implications for those who participate in HIV-related research. ... Loue and Pike have found a way to establish a united approach, addressing these issues through highlighting their commonly held beliefs and perspectives, and producing a beautifullyorchestrated volume where the realities of science dance in perfect tempo with the needs for protecting human rights.  ... important reading for numerous audiences ..." -Julianne M. Serovich, Ph.D., Columbus, Ohio. The Journal of Legal Medicine, 29 (2), 2008

Product details

• Assisted by: C Pike (Editor), C Pike (Editor), San Loue (Editor), Sana Loue (Editor), E. C. Pike (Editor), Earl C Pike (Editor), Earl C. Pike (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Hardback
• Released: 06.10.2007
• EAN: 9780387713618
• ISBN: 978-0-387-71361-8
• No. of pages: 344
• Dimensions: 158 mm x 239 mm x 26 mm
• Weight: 644 g
• Illustrations: XII, 344 p. 7 illus.
• Subjects: Humanities, art, music > Philosophy > General, dictionaries; Natural sciences, medicine, IT, technology > Medicine > General; C, Medicine, Medicine: general issues, Epidemiology & medical statistics, Public Health, health promotion, Public health & preventive medicine, Medical Ethics, Epidemiology, Health Sciences, Health Promotion and Disease Prevention, Theory of Medicine/Bioethics