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Informationen zum Autor Carani B. Sanjeevi is the editor of Immunology of Diabetes IV: Progress in Our Understanding, Volume 1079, published by Wiley. Toshiaki Hanafusa is the editor of Immunology of Diabetes IV: Progress in Our Understanding, Volume 1079, published by Wiley. Klappentext The incidence of diabetes in increasing all over the world and has become a major public health problem. This volume brings together reports from scientists working in the fields of immunology genetics that that report on basic research as well as current approaches to treatment in the clinic. Reports from workshops on autoantibodies and T cells are included, as are chapters covering target autoantigens, innate immunity in type 1 diabetes, fluminant type 1 diabetes, and the role of viral infections in type 1 diabetes. The genetics of LADA and SPIDDM are presented as well as a comparison of their immunoepidemiology and immunopathological features. A section on genetics and the characteristics of susceptible genes concludes the basic research. The clinical topices covered include islet regeneration and the use of stem cells in mediating tolerance for type 1 diabetes prevention. Reports on the progress on islet transplantation conclude the volume. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas . ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order ( www.nyas.org ). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member. Zusammenfassung The incidence of diabetes in increasing all over the world and has become a major public health problem. This volume brings together reports from scientists working in the fields of immunology genetics that that report on basic research as well as current approaches to treatment in the clinic. Inhaltsverzeichnis Part I: Special Papers:. 1. The Type 1 Diabetes Genetics Consortium: Stephen S. Rich, Patrick Concannon, Henry Erlich, Cecile Julier, Grant Morahan, Jorn Nerup, Flemming Pociot, John A. Todd. 2. A Mini Meta-Analysis of Studies on CD4+CD25+ T Cells in Human Type 1 Diabetes; Report of the Immunology of Diabetes Society T Cell Workshop: Timothy I.M. Tree, Bart O Roep and Mark Peakman. 3. HLA Class I Epitope Discovery in Type I Diabetes: Independent and Reproducible Identification of Proinsulin Epitopes of CD8 T-Cells. Gabrielle G. M. Pinkse, Christian Boitard, Timothy I.M Tree, Mark Peakman and Bart O. Roep. Part II: Diabetes in Asia:. 4. Genetics of Fluminant Type 1 Diabetes. Eiji Kawasaki, Katsumi Eguchi. 5. Why is Type 1 Diabetes Uncommon in Asia?: Yongsoo Park. 6. Association of SUMO4, as a Candidate Gene for IDDM5, with Susceptibility to Type 1 Diabetes in Asian Populations: Shinsuke Noso, Hiroshi Ikegami, Tomomi Fujisawa, Yumiko Kawabata, Katsuaki Asano, Yoshihisa Hiromine, Miyuki Moritani, Shigetaka Sugihara, Inkyu Lee, Eiji Kawasaki, Takuya Awata, Toshio Ogihara. 7. The Gene for Human IL-21 and Genetic Susceptibility to Type 1 Diabetes in Japanese: Katsuaki Asano, Hiroshi Ikegami, Tomomi Fujisawa, Yumiko Kawabata, Shinsuke Noso, Yoshihisa Hiromine, Toshio Ogihara. 8. Genetics of Type 1 Diabetes: Similarities and Differences Between Asian and Caucasian Populations: Hiroshi Ikegami, Tomomi Fujisawa, Yumiko Kawabata, Shinsuke Noso, Toshio Ogihara. Part III: Latent Autoimmune Diabetes in Adults (LADA):. 9. Immunopathological and Genetic Features in Slowly Progressive Insulin-Dependant Diabetes Mellitus (SPIDDM) and Latent Au...
