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Informationen zum Autor George P. Chrousos, MD, MACP, MACE, FRCP, is in the Unit of Endocrinology, Metabolism and Diabetes, First Department of Paediatrics, National University of Athens Medical School, Greece. He served as a Distinguished Visiting Scientist at the National Institute of Child Health and Human Development. He is among the most cited clinical investigators in the areas of Clinical Medicine, Biology and Biochemistry. Gregory A. Kaltsas, MD, FRCP, teaches at the Division of Endocrinology, Department of Pathophysiology, Medical School, National and Kapodistrian University of Athens, Greece. Klappentext Crosstalk between the neuroendocrine and immune systems plays an essential role in inflammatory, autoimmune, and allergic diseases. An international group of scientists from the fields of neurobiology, neuroendocrinology, immunology, and behavioral sciences reports here on recent advances in our understanding of the communication and modulation taking place between the neuroendocrine and immunological systems. In an effort to incorporate all recent knowledge in this field, broad aspects of endocrinology and neuropsychiatric and autoimmune disorders is included, with special attention given to recent progress in molecular biology and genetics. In particular, the volume focuses on diseases of the nervous system and their modulation by the immune and endocrine systems, as well as on the neuroimmunomodulation of inflammatory, autoimmune, and allergic diseases with an emphasis on the female gender. Special care has been taken by the editors to balance basic and clinical information. The volume is divided into sections: the cytokine and neuropeptide signal transduction systems and their immunomodulatory properties, the neuroendocrine immune basis of rheumatic disease, models of inflammation, the immunology of neuropsychiatric and allergic disorders, neuroendocrine and autoimmune adaptations in aging, neuroimmune interactions in chronic pain disorders and infectious diseases, and finally a structural and functional overview of the stress system. Clinical applications have been extrapolated from the basic knowledge and physiology of neuroimmune interactions, so this volume will provide a useful update for both researchers and clinicians. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas . ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order ( www.nyas.org ). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member. Zusammenfassung Crosstalk between the neuroendocrine and immune systems plays an essential role in inflammatory! autoimmune! and allergic diseases. Inhaltsverzeichnis Dedication of Smauel M. McCann: Chrousos. An Overview of the Volume: Chrousos. 1. Molecular Understanding of Cytokine-Steroid Hormones Dialogue: Implications for Human Diseases: Artz. 2. Chronology of Advances in Neuroendocrine Immunomodulation: McCann. 3. Regulation of Dendritic Cell Differentiation by Vasoactive Intestinal Peptide: Therapeutic Applications on Autoimmunity and Transplantation: Delgado. 4. ¿2-Adrenergic Receptors Decrease DNA Replication and Cell Proliferation and Induce Neurite Outgrowth in Transfected Rat Pheochromocytoma Cells: Flordelis. 5. Thymus-Dependent T Cell Tolerance of Neuroendocrine Functions: Principles, Reflections and Implications for Tolerogenic/Negative Self-Vaccination: Geenen. 6. Neuroendocrine Regulation of Skin Dendritic Cells: Granstein. 7. The Mitoc...
