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Continuing the research of the best-selling first edition, Patch-Clamp Analysis: Advanced Techniques, Second Edition collects three more years of research in the ever-expanding study of the cell membrane. With the latest developments in the "traditional" patch techniques such as whole-cell and single channel as well as perforated patch, fast drug application, loose patch and macropatch techniques, this authoritative second edition updates the standard techniques while introducing three brand new, cutting-edge technical advances in the field.
Thorough and timely, Patch-Clamp Analysis: Advanced Techniques, Second Edition is an invaluable resource for neuroscientists attempting to discover and understand the long-hidden complexities of the cell.
List of contents
Technology of Patch-Clamp Electrodes.- Whole-Cell Patch-Clamp Recordings.- Single-Channel Recording.- Combined Fluorometric and Electrophysiological Recordings.- Combining Uncaging Techniques with Patch-Clamp Recording and Optical Physiology.- Visually Guided Patch-Clamp Recordings in Brain Slices.- In Vivo Patch-Clamp Technique.- Perforated Patch-Clamp Techniques.- Fast Drug Application.- Pipette Internal Perfusion: Methods and Applications.- Loose-Patch-Clamp Method.- Recording Currents from Channels and Transporters in Macropatches.- Structure-Function Analyses of Single Cells by Combining Patch-Clamp Techniques with Reverse Transcription-Polymerase Chain Reaction.- Planar Patch Clamping.- Automated Glass Pipette-Based Patch-Clamp Techniques.
Summary
Continuing the research of the best-selling first edition, Patch-Clamp Analysis: Advanced Techniques, Second Edition collects three more years of research in the ever-expanding study of the cell membrane. With the latest developments in the “traditional” patch techniques such as whole-cell and single channel as well as perforated patch, fast drug application, loose patch and macropatch techniques, this authoritative second edition updates the standard techniques while introducing three brand new, cutting-edge technical advances in the field.
Thorough and timely, Patch-Clamp Analysis: Advanced Techniques, Second Edition is an invaluable resource for neuroscientists attempting to discover and understand the long-hidden complexities of the cell.
Additional text
From the reviews of the second edition:
"This book, edited by an outstanding expert in biophysics, and written by a large number of well-recognized contributors, is a complete text on this most important technique. … this excellent neuroscience book brings discussion of this most important technique up-to-date and discusses the current and future prospects in this field. … Patch clamp testing is becoming increasingly important in medical research. For this reason, this book can be highly recommended to medical-biological investigators." (Julian L. Ambrus and Clara M. Ambrus, The Journal of Medicine, February, 2008)
Report
From the reviews of the second edition:
"This book, edited by an outstanding expert in biophysics, and written by a large number of well-recognized contributors, is a complete text on this most important technique. ... this excellent neuroscience book brings discussion of this most important technique up-to-date and discusses the current and future prospects in this field. ... Patch clamp testing is becoming increasingly important in medical research. For this reason, this book can be highly recommended to medical-biological investigators." (Julian L. Ambrus and Clara M. Ambrus, The Journal of Medicine, February, 2008)
