Pulmonary Hypertension

This timely volume addresses the areas of pathophysiology and therapy of pulmonary hypertension, which have seen exciting developments over the past decade. The discoveries of endothelin overexpression as well as prostacyclin and nitric oxide deficiency in association with pulmonary hypertension have led to important therapeutic insights. In addition, the identification of genes associated with pulmonary hypertension has just begun to open the door to new pathophysiologic insights. The new therapies have led to significant improvements in patient function, quality of life and survival.
This book will be of interest not only to cardiologists, pulmonary specialists and rheumatologists, but also many nurses and pharmacotherapists are becoming increasingly involved in the therapy of patients with pulmonary hypertension.

List of contents

Historical Perspective: A Century of Primary (Idiopathic) Pulmonary Hypertension.- Classification of Pulmonary Hypertension.- Diagnostic Approach to Pulmonary Arterial Hypertension.- Pathophysiology of Pulmonary Arterial Hypertension.- Pulmonary Hypertension Genes.- The Right Ventricle in Pulmonary Hypertension.- Congenital Heart Disease Associated with Pulmonary Arterial Hypertension.- Connective Tissue Disease Associated Pulmonary Hypertension.- Pulmonary Hypertension Associated with HIV, Liver Disease, Sarcoidosis, and Sickle Cell Disease.- Chronic Thromboembolic Pulmonary Hypertension.- General Therapeutic Approach and Traditional Therapies.- Prostacyclin Therapy for Pulmonary Arterial Hypertension.- Endothelin and Its Blockade in Pulmonary Arterial Hypertension.- PDE5 Inhibitors and the cGMP Pathway in Pulmonary Arterial Hypertension.- Statins for Treatment of Pulmonary Hypertension.- Transitions and Combination Therapy for Pulmonary Arterial Hypertension.- Acute Right Ventricular Dysfunction: Focus on Acute Cor Pulmonale.- Lung Transplantation and Atrial Septostomy for Pulmonary Arterial Hypertension.- New Directions in Pulmonary Hypertension Therapy.

Summary

This timely volume addresses the areas of pathophysiology and therapy of pulmonary hypertension, which have seen exciting developments over the past decade. The discoveries of endothelin overexpression as well as prostacyclin and nitric oxide deficiency in association with pulmonary hypertension have led to important therapeutic insights. The new therapies have led to significant improvements in patient function, quality of life and survival. In this book, expert authors describe these new therapies. It will be of interest not only to cardiologists, pulmonary specialists and rheumatologists, but also many nurses and pharmacotherapists.

Additional text

From the reviews:
"This is a comprehensive review of pulmonary hypertension from pathophysiology to therapeutic options. … This book provides current, comprehensive, and clinical relevant information from pathophysiology to a wide range of therapeutic options. The intended audience includes cardiologists and pulmonary specialists, intensivists, and rheumatologists, as well as those healthcare professionals who face this clinical situation in their everyday practice. … This complete, up-to-date review of pulmonary hypertension covers all aspects of the disease from its pathophysiology to optimal therapeutic management." (Adriana Maria Rosario, Doody’s Review Service, September, 2008)
"It is thus timely to release an up-dated textbook to the growing number of physicians who have an interest in pulmonary vascular medicine. Pulmonary Hypertension will undoubtedly provide useful information on the condition to readers. ... will be very helpful to the busy clinician who is treating patients with pulmonary hypertension. ... There is no doubt that this book will be of interest to nurses, medical trainees, and physicians from various fields who witness the burden of pulmonary hypertension in their practice." (Marc Humbert, The New England Journal of Medicine, November, 2008)
“For those who want a comprehensive, concise but not repetitive review of pulmonary hypertension with up to date review of therapy, this book is it. A well done review of the subject from history, diagnosis, genetics to chapters on the newest therapies. … It reads well, can be read in one session for an overview or studied carefully for those interested in a thorough introduction to the field. … A good additions to one’s library covering a very specialized field.” (John Somberg, American Journal of Therapeutics, June, 2010)

Report

From the reviews:

"This is a comprehensive review of pulmonary hypertension from pathophysiology to therapeutic options. ... This book provides current, comprehensive, and clinical relevant information from pathophysiology to a wide range of therapeutic options. The intended audience includes cardiologists and pulmonary specialists, intensivists, and rheumatologists, as well as those healthcare professionals who face this clinical situation in their everyday practice. ... This complete, up-to-date review of pulmonary hypertension covers all aspects of the disease from its pathophysiology to optimal therapeutic management." (Adriana Maria Rosario, Doody's Review Service, September, 2008)
"It is thus timely to release an up-dated textbook to the growing number of physicians who have an interest in pulmonary vascular medicine. Pulmonary Hypertension will undoubtedly provide useful information on the condition to readers. ... will be very helpful to the busy clinician who is treating patients with pulmonary hypertension. ... There is no doubt that this book will be of interest to nurses, medical trainees, and physicians from various fields who witness the burden of pulmonary hypertension in their practice." (Marc Humbert, The New England Journal of Medicine, November, 2008)
"For those who want a comprehensive, concise but not repetitive review of pulmonary hypertension with up to date review of therapy, this book is it. A well done review of the subject from history, diagnosis, genetics to chapters on the newest therapies. ... It reads well, can be read in one session for an overview or studied carefully for those interested in a thorough introduction to the field. ... A good additions to one's library covering a very specialized field." (John Somberg, American Journal of Therapeutics, June, 2010)

Product details

• Authors: Harrison W Farber, Harrison W. Farber, Nicholas Hill, Nicholas S Hill, Nicholas S. Hill
• Assisted by: Harrison W. Farber (Editor), Nicholas S. Hill (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Hardback
• Released: 17.04.2009
• EAN: 9781588296610
• ISBN: 978-1-58829-661-0
• No. of pages: 444
• Weight: 801 g
• Illustrations: XV, 444 p.
• Series: Contemporary Cardiology; Contemporary Cardiology
• Subject: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine