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Informationen zum Autor Suresh Rattan is a biogerontologist - a researcher in the field of biology of ageing, biogerontology. Peter Kristensen is the editor of Understanding and Modulating Aging, Volume 1067, published by Wiley. Klappentext For the last 40 years, biogerontology--the study of the biological basis of aging--has progressed tremendously, and it has now become an independent and respected field of study and research. This volume brings together contributions by biogerontologists, bioethicists, biodemographers, researchers, students, clinicians, and dieticians. The main areas of discussion and presentation of new research results include (1) biological and non-biological factors affecting lifespan and the quality of life; (2) ethical and social issues related to lifespan and health-span extension; (3) physiological, cellular, and molecular aspects of aging; (4) new technologies to understand and modulate aging; (5) the latest successful approaches in the prevention and treatment of age-related diseases, and (6) aging intervention, prevention, and modulation by genes, natural and synthetic molecules, and lifestyle modifications. Accordingly, the main sections of the volume focus on the following topics: defining aging, longevity, and the diseases of aging; selected aging organs; cellular aging; molecular aging; ethics of aging intervention; genetics of aging and longevity; and aging interventions. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member. Zusammenfassung For the last 40 years! biogerontology-the study of the biological basis of aging-has progressed tremendously! and it has now become an independent and respected field of study and research. This volume brings together contributions by biogerontologists! bioethicists! biodemographers! researchers! students! clinicians! and dieticians. Inhaltsverzeichnis Introduction: Suresh I.S. Rattan, Peter Kristensen, Brian F.C. Clark. 1. Aging is No Longer an Unsolved Problem in Biology. Robin Holliday. 2. Free Radical theory of Aging: an Update, and increasing the Functional Life Span. Denham Harman. 3. The Free Radical Phantasm: A Panoply of Paradoxes. Randolph M. Howes. 4. Catabolic insufficiency and Aging. Alexei Terman. 5. Methionine Sulfoxide Reductases: Relevance to Aging and Protection Against Oxidative Stress. Filipe Cabreiro, Cédric R. Picot, Bertrand Friguet, Isabelle Petropoulos. 6. Inadequate Intensity of Various Components of Total Environmental Signals Can Lead to Natural Aging. Alexander V. Khalyavkin, anatoli I Yashin. 7. Cellular Redox Regulation and Pro-Oxidant Signalling Systems: A New Perspective on the Free Radical theory of Aging. anthony W. Linnane, Hayden Eastwood. 8. Human Immunosenescence: Does it Have an infectious Component?. G. Pawelec, S. Koch, C. Franceschi, A. Wikby. 9. Aging in Mouse and Human Systems: a Comparative Study. Lloyd Demetrius. 10. Extrapolaholics anonymous: Why Demographers' Rejections of A Huge Rise in Cohort Life Expectancy This Century Are Overconfident. Aubrey D.N.J. De Grey. 11. The Value of Life and the Value of Life Extension. Steven Horrobin. 12. Oxphos Supercomplexes: Respiration and Lifespan Control in the Aging Model. Podospora anserina Frank Krause, Christian Q. Scheckhuber, Alexandra Werner, Sascha Rexroth, Nicole H. Reifschneider, Norbert A. Dencher, Heinz D...
