Cell Culture and Upstream Processing

Informationen zum Autor Michael Butler-Associate Dean of Science; Professor of Cell Technology! Department of Microbiology! School of Science! University of Manitoba! Winnipeg! Canada Klappentext Each chapter in Cell Culture and Upstream Processing is taken from a presentation at the highly acclaimed IBC conferences and describe ways for scientists to improve yield and optimize the cell culture production process for biopharmaceuticals! by focusing on safety! quality! economics and operability and productivity issues. Zusammenfassung Each chapter in Cell Culture and Upstream Processing is taken from a presentation at the highly acclaimed IBC conferences and describe ways for scientists to improve yield and optimize the cell culture production process for biopharmaceuticals, by focusing on safety, quality, economics and operability and productivity issues. Inhaltsverzeichnis 1. Cell Line Development and Culture Strategies: Future Prospects to Improve Yields 2. Use of DNA Insulator Elements and Scaffold / Matrix-Attached Regions for Enhanced Recombinant Protein Expression 3. Targeted Gene Insertion to Enhance Protein Production From Cell Lines 4. Recombinant Human IgG Production From Myeloma and Chinese Hamster Ovary Cells 5. Cell Culture Media Development: Customization of Animal Origin-Free Components and Supplements 6. Post-Translational Modification of Recombinant Proteins 7. Metabolic Engineering to Control Glycosylation 8. An Alternative Approach: Humanization of N-glycosylation Pathways in Yeast 9. Perfusion or Fed-Batch? A Matter of Perspective

Product details

• Authors: M. Butler, Michael Butler, Michael (University of Manitoba Butler, Butler m
• Assisted by: Michael Butler (Editor), Michael (University of Manitoba Butler (Editor)
• Publisher: Taylor & Francis Ltd.
• Languages: English
• Product format: Paperback / Softback
• Released: 29.03.2007
• EAN: 9780415399692
• ISBN: 978-0-415-39969-2
• No. of pages: 204
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Pharmacy; SCIENCE / Life Sciences / General, SCIENCE / Life Sciences / Biochemistry, SCIENCE / Biotechnology, SCIENCE / Life Sciences / Cell Biology, SCIENCE / Life Sciences / Microbiology, molecular biology, biotechnology, Cellular biology (cytology)