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Memory can be typically de?ned as the brain function enabling the encoding, storage and retrieval of sensory information. In operational terms, this de?nition implies that our central nervous system not only processes various sensory modalities, be they visual, tactile, auditory, olfactory or gustatory, but is also capable of forming, organizing and conserving memory traces for extended periods of time. At both psychological and physiological levels, there is now a consensus that memory must no longer be seen as a unitary phenomenon but rather as an ensemble of dynamic processes, each one being subserved by different brain regions organized into multiple memory systems that support different forms of memory and that constantly interact to ensure optimal performance during any given cognitive challenge. Despite remarkable progress achieved over the last 30 years in our understanding of the neural bases of cognitive processes and associated pathologies, the questions of how, where and when memory traces are formed in the brain remain central issues and continue to fuel much debate in the ?eld of cognitive neuroscience.
List of contents
The Neuroanatomy and Neuropsychology of Declarative and Nondeclarative Memory.- Dynamics of Hippocampal-Cortical Interactions During Memory Consolidation: Insights from Functional Brain Imaging.- From Molecule to Memory System: Genetic Analyses in Drosophila.- Towards a Molecular and Cellular Understanding of Remote Memory.- Post-Activation State: A Critical Rite of Passage of Memories.- Reactivation-Dependent Amnesia: Disrupting Memory Reconsolidation as a Novel Approach for the Treatment of Maladaptive Memory Disorders.- The Organizing Principles of Real-Time Memory Encoding: Neural Clique Assemblies and Universal Neural Codes.- Making and Retaining New Memories: The Role of the Hippocampus in Associative Learning and Memory.- Entorhinal Grid Cells and the Representation of Space.- The Prefrontal Cortex: Categories, Concepts, and Cognitive Control.- Molecules that Disrupt Memory Circuits in Alzheimer's Disease: The Attack on Synapses by A? Oligomers (ADDLs).
Summary
Memory can be typically de?ned as the brain function enabling the encoding, storage and retrieval of sensory information. In operational terms, this de?nition implies that our central nervous system not only processes various sensory modalities, be they visual, tactile, auditory, olfactory or gustatory, but is also capable of forming, organizing and conserving memory traces for extended periods of time. At both psychological and physiological levels, there is now a consensus that memory must no longer be seen as a unitary phenomenon but rather as an ensemble of dynamic processes, each one being subserved by different brain regions organized into multiple memory systems that support different forms of memory and that constantly interact to ensure optimal performance during any given cognitive challenge. Despite remarkable progress achieved over the last 30 years in our understanding of the neural bases of cognitive processes and associated pathologies, the questions of how, where and when memory traces are formed in the brain remain central issues and continue to fuel much debate in the ?eld of cognitive neuroscience.
