CtBP Family Proteins

This book is a comprehensive monograph on the CtBP family proteins. These proteins are gaining wide scientific interest due to their critical roles in animal development and in oncogenesis. The CtBP family proteins are multifunctional. They predominantly function as transcriptional corepressors in the nucleus by recruiting various histone modifying enzymes such as histone deacetylases, histone methylases and a histone demethylase. They also perform several diverse cytosolic functions such as Golgi maintenance and in central nervous system synapses.

List of contents

CtBP Family Proteins: Unique Transcriptional Regulators in the Nucleus with Diverse Cytosolic Functions.- Transcriptional Repression by the CtBP Corepressor in Drosophila.- CtBP and Hematopoietic Transcriptional Regulators.- CtBP: A Link between Apoptosis and the Epithelial-Mesenchymal Transition.- The Significance of the CtBP AdE1A Interaction during Viral Infection and Transformation.- CtBP Proteins in Vertebrate Development.- CtBP as a Redox Sensor in Transcriptional Repression.- CtBP Corepressor Complex A Multi-Enzyme Machinery that Coordinates Chromatin Modifications.- Structural Determinants of CtBP Function.- CtBP3/BARS and Membrane Fission.- CtBPs as Synaptic Proteins.- A New Member of the CtBP/BARS Family from Plants: Angustifolia.

Summary

The Ctbp family proteins are multifunctional. They predominantly function as transcriptional corepressors in the nucleus by recruiting various histone modifying enzymes such as histone deacetylases, histone methylases and a histone demethylase. This book is a comprehensive monograph on the Ctbp family proteins.

Product details

• Assisted by: Chinnadurai (Editor), G Chinnadurai (Editor), G. Chinnadurai (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Hardback
• Released: 01.01.2006
• EAN: 9780387399713
• ISBN: 978-0-387-39971-3
• No. of pages: 121
• Dimensions: 160 mm x 14 mm x 236 mm
• Illustrations: IX, 121 p. 38 illus., 3 illus. in color.
• Series: Molecular Biology Intelligence Unit; Molecular Biology Intelligence Unit
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Clinical medicine; B, Biomedical and Life Sciences, Cellular biology (cytology), Medical Microbiology, Cell Biology