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Informationen zum Autor Alan Crozier is Professor of Plant Biochemistry and Human Nutrition in the Institute of Biomedical and Life Sciences at the University of Glasgow, UK, Mike Clifford is Professor of Food Safety in the School of Biomedical and Molecular Sciences at the University of Surrey, UK, and Hiroshi Ashihara is Professor of Plant Biochemistry in the Department of Biology at Ochanomizu University, Tokyo, Japan. Contributors to the book: Dr Michael H Beale Dr Kirsten Brandt Dr Lars P Christensen Dr Jennifer L Donovan Professor Peter J Facchini Dr Richard M Faulks Professor Glenn R Gibson Dr Andrew J Humphrey Dr Indu B Jaganath Dr Paul A Kroon Dr David K Liscombe Dr Claudine Manach Dr Serena Marks Professor Richard Mithen Dr Michael Saltmarsh Dr Kieran M Tuohy Dr Takao Yokota Dr Katherine G Zulak Klappentext Plant secondary metabolites have been a fertile area of chemical investigation for many years, driving the development of both analytical chemistry and of new synthetic reactions and methodologies. The subject is multi-disciplinary with chemists, biochemists and plant scientists all contributing to our current understanding. In recent years there has been an upsurge in interest from other disciplines, related to the realisation that secondary metabolites are dietary components that may have a considerable impact on human health, and to the development of gene technology that permits modulation of the contents of desirable and undesirable components. Plant Secondary Metabolites: Occurrence, Structure and Role in the Human Diet addresses this wider interest by covering the main groups of natural products from a chemical and biosynthetic perspective with illustrations of how genetic engineering can be applied to manipulate levels of secondary metabolites of economic value as well as those of potential importance in diet and health. These descriptive chapters are augmented by chapters showing where these products are found in the diet, how they are metabolised and reviewing the evidence for their beneficial bioactivity. Zusammenfassung Plant secondary metabolites have been a fertile area of chemical investigation for many years! driving the development of both analytical chemistry and of new synthetic reactions and methodologies. The subject is multi-disciplinary with chemists! biochemists and plant scientists all contributing to our current understanding. Inhaltsverzeichnis Contributors. 1 Phenols, Polyphenols and Tannins: An Overview ( Alan Crozier, Indu B. Jaganath and Michael N. Clifford ). 1.1 Introduction. 1.2 Classification of phenolic compounds. 1.3 Biosynthesis. 1.4 Genetic engineering of the flavonoid biosynthetic pathway. 1.5 Databases. 2 Sulphur-Containing Compounds ( Richard Mithen ). 2.1 Introduction. 2.2 The glucosinolates-myrosinase system. 2.3 Chemical diversity of glucosinolates in dietary crucifers. 2.4 Biosynthesis. 2.5 Genetic factors affecting glucosinolate content. 2.6 Environmental factors affecting glucosinolate content. 2.7 Myrosinases and glucosinolate hydrolysis. 2.8 Hydrolytic products. 2.9 Metabolism and detoxification of isothiocyanates. 2.10 The Alliin-alliinase system. 2.11 Biological activity of sulphur-containing compounds. 2.12 Anti-nutritional effects in livestock and humans. 2.13 Beneficial effects of sulphur-containing compounds in the human diet. 3 Terpenes ( Andrew J. Humphrey and Michael H. Beale ). 3.1 Introduction. 3.2 The biosynthesis of IPP and DMAPP. 3.3 Enzymes of terpene biosynthesis. 3.4 Isoprenoid biosynthesis in the plastids. 3.5 Isoprenoid biosynthesis in the cytosol. 3.6...
