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Informationen zum Autor Nigel Webster graduated in Medicine from Leeds University in 1977 and obtained his PhD in 1985. He was appointed to the Chair in Anaesthesia & Intensive Care at the University of Aberdeen, in 1994. Professor Webster has an extensive publication record in inflammatory and immune responses in the critically ill. He reviews for a number of basic science, anaesthesia and critical care journals and is an Editorial Board member for the British Journal of Anaesthesia and Critical Care Medicine. Helen Galley obtained her PhD from the University of Leeds in 1989. She was appointed to the post of Lecturer in Anaesthesia & Intensive Care at the University of Aberdeen in 1995 and was promoted to Senior Lecturer in 2000. Dr Galley has published 60 research papers, 26 reviews/editorials/chapters and edited 12 books. Her research interests focus on inflammatory and immune responses in the critically ill. Dr Galley reviews for a number of basic science, anaesthesia and critical care journals and is a member of the Board of Management for the British Journal of Anaesthesia. Klappentext Anaesthesia Science presents the scientific foundations upon which the clinical practice of anaesthesia and care of the critically ill are based. Written on the basis that basic science underlies the practice of anaesthesia, Anaesthesia Science provides detailed coverage on less well appreciated aspects of the subject, such as the microcirculation, multi-organ failure, and the theory of pain. The book thoroughly integrates the clinical practice of anaesthesia with basic sciences, providing all the information needed in one convenient source. Furthermore the contributors, who feature some of the world's most eminent anaesthesiologists, consistently include salient features of the scientific foundations of anaesthesia in their discussions. Anaesthesia Science is based on the Fellowship of the Royal College of Anaesthetists (FRCA) syllabus and aimed at trainee anaesthetists preparing for the FRCA, the European Diploma of Anaesthesiology and other equivalent examinations. Zusammenfassung Anaesthesia Science Edited by Nigel R. Webster BSc, MBChB, PhD, FRCA, FRCP, FRCS Chair, Academic Unit of Anaesthesia & Intensive Care, School of Medicine, University of Aberdeen, Aberdeen, UK Helen F. Inhaltsverzeichnis Part 1: Pharmacology . 1 Pharmacokinetic principles. Michel MRF Struys, Alain Kalmar and Peter De Paepe . 2 Pharmacodynamics. Susan Hill . 3 Pharmacogenomics. Amr Mahdy . 4 Receptors and second messenger systems. Thomas Engelhardt. 5 Anaphylaxis. Michael Rose and Malcolm Fisher . 6 Refl ections on chirality. Daniel Burke . 7 Ion channels. George Lees, Leanne Coyne and Karen M. Maddison . 8 Immunosuppression. Roxanna Bloomfield and David Noble . 9 Mechanisms of anaesthesia: a role for voltage-gated K channels?. Peter Århem, Kristoffer Sahlholm and Johanna Nilsson . 10 Use and abuse of antibiotics. Jeremy Cohen and Jeffrey Lipman . Part 2: Physiology . 11 Infl ammation and immunity. Helen F. Galley . 12 Shock: pathogenesis and pathophysiology. Anand Kumar . 13 Cellular physiology. Nigel R. Webster . 14 Acid-base balance: albumin and strong ions. John A. Kellum . 15 Fluids and electrolytes. Martin Kuper and Neil Soni . 16 The microcirculation. Bryce Randalls . 17 Respiratory physiology at the molecular level. Andrew Lumb . 18 Non-respiratory functions of the lung. Andrew Lumb and Susan Walwyn . 19 The brain as a site of infl ...
