Biomaterials and Regenerative Medicine in Ophthalmology

Biomaterials and Regenerative Medicine in Ophthalmology, 3rd Edition is thoroughly revised and expanded, including 8 new chapters which offer greater focus on corneal and retinal reconstruction, using specialised ophthalmic biomaterials. The book is divided into five essential parts, beginning with an introduction and outlining the biomaterial-ocular surface interface, laying the foundation with materials, properties, tissue interaction, and design coverage. The subsequent sections systematically cover strategies for reconstruction, before exploring other applications, as well as industry and clinical perspectives. Detailed methods for the design and development of ophthalmic biomaterials are outlined, along with supporting industry and clinical case studies, to offer practical insights and allow for improved translation into research and therapeutics. Biomaterials and Regenerative Medicine in Ophthalmology, 3rd Edition is suitable for researchers, academics, and postgraduate students wanting to gain a deeper understanding of ophthalmic biomaterials and regenerative medicine in ophthalmology. This book may also be of interest to R&D groups developing novel ophthalmic biomaterials, as well as clinicians and ophthalmologists with an interest in biomaterials and regenerative strategies.

List of contents

Part One: Biomaterial-Ocular Surface Interface
1. Ocular biotribology and the ocular/contact lens interface
2. The ageing tear film and ocular surface: biomaterials challenges
3. The design and development of hydrogels and silicone hydrogels for contact lens applications
4. Advances in contact lens design

Part Two: Strategies for Corneal Reconstruction
5. The strengths and limitations of primary corneal cells
6. Potential for corneal cells from iPS cells
7. Biomaterials for repairing the corneal epithelium
8. Biomaterials for stromal reconstruction
9. Kuragel - Liquid cornea
10. Biomaterials for corneal endothelial cell transplantation

Part Three: Strategies for Retinal Reconstruction
11. Biomaterials for retinal tissue engineering
12. Neural retina
13. RPE and choroid
14. Optic nerve

Part Four: Biomaterials for Ocular Drug Delivery
15. Topical delivery of ophthalmic drugs
16. Slow-release drug platforms for ophthalmology
17. Slow-release glaucoma drug delivery systems
18. Intra-vitreal drug delivery

Part Five: Other Applications
19. Hydrogels for ophthalmological use: physiochemical and structural considerations
20. Polymer science in glaucoma implants
21. Advances in intraocular lenses
22. Vitreal substitutes
23. Keratoprotheses
24. Orbital implants
25. Retinal prostheses - lessons learned
26. IOP monitoring systems

About the author

Prof Damien Harkin is a Professor at the Centre for Vision and Eye Research, Queensland University of Technology, Queensland, Australia. He is an experienced teacher and medical researcher, in the areas of human structure, function and disease His main area of research focus for the last 20 years has been the development of cell and tissue therapies for the treatment of common and severe eye diseases. This research has been supported by over $3M dollars in research funding and has led to over 80 publications in peer-reviewed journals and book chapters. Professor Harkin received his BSc and PhD (Pathology) from the University of Adelaide (1993) before completing postdoctoral training at Harvard Medical School (1994-1996) and the University of Melbourne (1997). He commenced working at QUT as a lecturer in 2001 and was promoted to Professor in 2016. Professor Harkin also holds honorary positions at the Queensland Eye Institute (since 2005) and Australian Red Cross LifeBlood (since 2020).Dr Katelyn Swindle-Reilly is an Associate Professor and College of Engineering Innovation Scholar, The Ohio State University, Ohio, USA. She is tenured faculty with appointments in Biomedical Engineering, Chemical and Biomolecular Engineering, and Ophthalmology and Visual Sciences at The Ohio State University. She has degrees in Chemical Engineering, with a B.S. from Georgia Institute of Technology, and M.S. and Ph.D. from Washington University in St. Louis. She has managed multiple research projects from initial research phase through manufacturing and regulatory approval, including serving as Chief Technology Officer of an ophthalmic startup company. Dr. Swindle-Reilly’s research lab focuses on the design of polymeric biomaterials for soft tissue repair and drug delivery with focused applications in ophthalmology.Dr. Ramesh Ayyala, MD, FRCS, FRCOphth is a world-renowned ophthalmologist and is the Professor and Chair of Ophthalmology at the University of South Florida, Tampa, FL, USA, where he also holds the James P. and Heather Gills Chair in Ophthalmology. Prior to USF, Dr. Ayyala was a tenured professor of ophthalmology, director of the glaucoma service, and residency/fellowship director at Tulane University. He is a graduate of Gandhi Medical College, Osmania University in Hyderabad. He received his residency training in ophthalmology at Mersey Region Hospitals, United Kingdom (UK), and at USF, Tampa, FL. Dr. Ayyala completed his glaucoma fellowship at Massachusetts Eye and Ear, Harvard Medical School and his cornea/external disease fellowship at Boston University Medical Center. Dr. Ayyala is board certified on three continents (India, UK and USA), a fellow of the Royal College of Ophthalmology (Lon) and the Royal College of Surgeons (Edinburgh), and the American Academy of Ophthalmology. He is a past president of the Louisiana Academy of Eye Physicians and Surgeons.

Product details

• Assisted by: Ramesh Ayyala (Editor), Harkin Damien (Editor), Katelyn Swindle-Reilly (Editor)
• Publisher: Elsevier
• Languages: English
• Product format: Paperback / Softback
• Release: 01.06.2026
• EAN: 9780443366437
• ISBN: 978-0-443-36643-7
• Series: Woodhead Publishing Series in Biomaterials
• Subjects: Natural sciences, medicine, IT, technology > Technology > General, dictionaries; MEDICAL / Biotechnology, TECHNOLOGY & ENGINEERING / Biomedical, biotechnology, Materials science, Biomedical engineering, TECHNOLOGY & ENGINEERING / Materials Science / General, Biomedical engineering / Medical engineering