Motor Control Methods and Clinical Applications

Motor Control Methods and Clinical Applications provides a detailed review on the use of non-invasive brain stimulation to study motor control. Split into two distinct parts, this new volume covers the latest research in motor control, including real examples of these methods in a clinical setting. The first part covers advanced methods such as transcranial magnetic, electrical and ultrasound stimulation, long latency, spinal reflexes, multichannel EMG, and EEG-EMG analyses that can be used to examine and modulate the motor system. The second part of the book addresses the clinical applications of these methods.

List of contents

Part 1 Methods
1. Transcranial magnetic stimulation: positive effects (includes single and paired pulse methods, and triple-stimulation-technique)
2. Transcranial magnetic stimulation: negative motor effects (contralateral and ipsilateral silent periods)
3. Modulation of TMS motor-evoked potentials by muscle contraction, motor imagery, action observation, action preparation
4. Effect of non-invasive brain stimulation on voluntary movements (such as effects on RT, ballistic movement, kinematic effects, with TMS, including TES if appropriate)
5. Induction of motor system plasticity using transcranial magnetic stimulation (e.g., regular rTMS, TBS, PAS, QPS, sTMS etc)
6. Induction of motor system plasticity using transcranial electrical stimulation (tDCS, tACS, random noise stimulation
7. Induction of motor system plasticity using transcranial ultrasound stimulation
8. Induction of motor system plasticity using temporal interference stimulation
9. Contributions of spinal epidural recordings to mechanisms of TMS and TES
10. Corticomuscular or EEG-EMG coherence, and intermuscular or EMG-EMG coherence
11. TMS-EEG - relation to motor physiology
12. ERD/ERS, BP (EEG/MEG), multichannel surface EMG, EMG-EEG backaveraging
13. Brain computer interfaces in the motor system: the technologies
14. Long-latency reflexes and cutaneous reflexes
15. Brainstem reflexes and startle reaction
16. Spinal reflexes (H-reflex, reciprocal inhibition)

Part 2: Clinical Applications:
17. Utility of TMS in the diagnosis of neurological disorders
18. Electrophysiological studies in the diagnosis of movement disorders (multiple channel surface EMG, EMG-EEG backaveraging, for tremor, muscle jerks/myoclonus)
19. Clinical use of TMS-EEG in the motor system
20. Clinical applications of ultrasound neuromodulation of the motor system
21. Clinical application of rTMS/tDCS as treatment in motor disorders (e.g. ALS, PD)
22. Clinical applications of Brain computer interfaces in the motor system

About the author

Dr. Robert Chen received MA and medical degrees (MBBChir) from the University of Cambridge and M.Sc. from the University of Toronto. He undertook Neurology residency at the Western University, and fellowship at the National Institute of Neurological Disorders and Stroke. He is currently Professor of Medicine (Neurology) at the University of Toronto, the Catherine Manson Chair in Movement Disorders, Senior Scientist at the Krembil Brain Institute, a full member of the Institute of Medical Science at the University of Toronto, Editor-in-Chief of the Canadian Journal of Neurological Sciences and Associate Editor for Movement Disorders. His research interests include human motor physiology, brain plasticity and understanding the pathophysiology and development of new treatments for movement disorders such as Parkinson’s disease and dystonia. He has published over 350 research papers with Google Scholar H-index of over 100.Prof. Ulf Ziemann is the Director of Department Neurology & Stroke and a Co-Director of the Hertie-Institute for Clinical Brain Research, University of Tübingen, Germany. He has been the Editor-in-Chief of Clinical Neurophysiology (2016-2023) and is a Deputy Editor of Brain Stimulation. His main research topics are motor cortex, plasticity, non-invasive brain state-dependent stimulation, TMS-EEG, and neuropharmacology. His clinical expertise focuses on stroke, neuroimmunology and clinical neurophysiology. He has received numerous award, including the Richard-Jung Prize of German Society of Clinical Neurophysiology, a National Institutes of Health (NIH) Merit Award, and is a Clarivate Web of Science Highly Cited Researcher (2020-2023).

Product details

• Assisted by: Chen Robert (Editor), Ziemann Ulf (Editor)
• Publisher: Elsevier
• Languages: English
• Product format: Hardback
• Release: 01.07.2026
• EAN: 9780443274428
• ISBN: 978-0-443-27442-8
• Series: Handbook of Clinical Neurology
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine; MEDICAL / Neurology, Neurology & clinical neurophysiology, Neurology and clinical neurophysiology