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The book demonstrates the designing and novel supramolecular self-assembly carbon nanomaterial's as stimuli-responsive drug delivery platforms for cancer therapy through its chapters.This book provides some achievements in the use of CBNMs for biomedical applications. Moreover, in this book we also focus on some recently found key features of CBNMs and their utilization for superior bio-applications. However, as CBNMs still contain toxicity, more systematic studies are needed to determine the toxicity and pharmacokinetics of CBNMs.
The book discusses Carbon-based nanomaterials (CBNMs) have attracted substantial research interest in biomedical sciences and nanobiotechnological, rendered from its unique structure, electronic, mechanical, and optical properties. By taking advantage of such aspects in a single entity, CBNMs could be used for developing biomedical applications in future. Results so far have shown that proper fictionalization is essential to yield biocompatible CNMs which are able to deliver either drugs or genes into brain through local or systemic injection. In this book special emphasis is placed on the implications of these interaction modes to design novel stimuli-responsive drug delivery principles and concepts, aiming to enhance the spatial, temporal, and dosage precision of drug delivery to cancer cells.
The book has been satisfying the biomedical applications of carbon-based nanomaterials (CBNMs) in drug delivery for cancer diagnosis and therapy. As a future perspective, the advantages and disadvantages of CBNMs should be weighed against that of other drug delivery systems since each of these systems has pros and cons considering the type of disease, delivery path, drug molecule properties, and DNA sequence. Finally, future perspectives are discussed to highlight current challenges and future opportunities in self-assembly-based stimuli-responsive drug delivery nanotechnologies for cancer therapy.
List of contents
Foreword. Preface. Acknowledgment. About the author. Introduction. Summary. Chapter 1Recent Developments and Future Prospects In vitro and In vivo of CNTs Nanocarriers for-Targeted Drug Delivery System. Chapter 2 Carbon Nanotubes as Targeting Therapeutic Arsenal for Blood Brain Cancer Tumors Diseases-Based Novel Drug Delivery Platforms. Chapter 3 Carbon Nanomaterials as Emerging Nanocarriers for the Anti-Cancer Targeting Drug Delivery Doxorubicin: Improved Novel Cancer Therapy Technologies. Chapter 4 Novel Technologies Toward Intervention Carbon Family-Based Nanomaterials for Detection, Diagnosis and Cancer Therapeutics. Chapter 5 Pharmacokinetics, Biodistribution and Intracellular Energy Metabolism Aspects of Carbon Nanomaterials: Improving Novel Outcomes of Functionalization for Biomedical Applications. Chapter 6 Cytotoxicity Profile of Carbon Nanomaterials as an Effective Anticancer Drug Carriers. Chapter 7 Novel Tumor-Targeting Drug Delivery Systems Based- Carbon Nanomaterials in Cancer Treatment. Chapter 8 Carbon-Based Nanomaterials (CBNMs) as Emerging Platform for Anticancer Nanotherapy: Novel Strategy and Future Prospects. Chapter 9 Recent Advancements of Carbon Dots Strategy Based Effective Novel Photosensitizers and Anticancer Drug Delivery System. References. Index.
About the author
LOUTFY H. MADKOUR is a Full Professor of Physical chemistry, Nanoscience and Nanotechnology at Tanta University (Egypt) and Al Baha University (Saudi Arabia). .He is a contributing Researcher and Editor to Chemistry World. He has more than 20 years of experience in science: research, writing and editing in condensed-matter, Corrosion Science and Advanced Structured Materials relating to Nanoscience, Nanomaterials, Technology/Nanotechnology/Biotechnology, Cancer Nanomedicine, and Drug Delivery. He received his BSc, MSc, and PhD in Physical Chemistry from the Cairo, Minia, and Tanta Universities in Egypt, respectively. (h-index 24, Scopus Author ID: 57201889680, 2145 citations). He has conducted a series of studies in various areas of the field of Physical chemistry: electrochemistry, electroanalytical chemistry, corrosion science, density functional theory (DFT), molecular dynamic simulation, quantum chemistry, theoretical chemistry, chemical equalization principles, nanoscience, nanotechnology, nanomedicine, nanotoxicology, electrometallurgy, analytical chemistry, polarography, electrolytic extraction of heavy metals from natural ores and deposits, electrochemical thermodynamics, and environmental chemistry. His earlier research included the biosynthesis of metallic nanoparticles (MNPs) as well as toxicology studies for pharmacological applications in nanomedicine and therapy. He has published 200 peer-reviewed original research articles, 26 review articles, 8 book chapters and 12 books in the area of physical and environmental chemistry, advanced structural nanomaterials, corrosion science, nanoelectronics materials, advancements and Innovations in energy storage, cancer nanomedicine, drug delivery and nanotoxicology.
Prof. MADKOUR is appointed as the prestigious Editorial Board member of several international journals. His name has been listed in the top 2% of the most distinguished and influential scientists globally according to the ranking and database of Stanford American University of Scientists globally in (2022). He obtained Award: ISAO in the year (2022): "Lifetime Achievement Award" in the International Scientist Awards on Engineering, Science and Medicine. He obtained Awards: ISAO in the years (2022, 2021 and 2020): "Distinguished Scientist Award" in the International Research Awards on Science, Technology, and Management.
