Immune Response in the Critically Ill

List of contents

The Four Ds of the Danger Model: Distress, Damage, Destruction, and Death.- The Immune Response in Critical Illness: Excessive, Inadequate or Dysregulated.- Genomics of the Sepsis Syndrome.- The Pro-Inflammatory Cytokine Cascade.- Inhibitory Cytokines.- Interleukin-1? and Interleukin-18: Two Cytokine Precursors for Interleukin-1? Converting Enzyme (Caspase-1).- Bacterial Toxins Induce Specific Cytokine Patterns In Vivo and In Vitro.- The Acute Phase Response and Enhancing Resistance to Bacterial Infection.- Cytokines as Mediators of Lung Innate Immunity.- Fetuin Opsonizes Macrophage-Deactivating Cations.- LPS Receptors.- Regulation of Cellular Responses to Bacterial Endotoxin.- The Role of Nitric Oxide in the Initiation of Inflammation in Shock.- Regulation of Neutrophil Activation in Acute Lung Injury and SIRS.- Neutrophils and Acute Lung Injury.- Lymphocyte Activation, Anergy, and Apoptosis in Polymicrobial Sepsis.- Trauma Mediators Favor Differentiation of Monocytes to Macrophage Rather Than to Dendritic Cells.- Programmed Cell Death (Apoptosis) and the Immunologic Derangements of Critical Illness.- The Interaction Between the Coagulation System and the Systemic Inflammatory Mediators.- The Endothelium as an Immune Organ: Active Player and Passive Target.- Immunoregulation in Shock, Trauma, and Sepsis.- Endotoxemia in Healthy Subjects as a Human Model of Inflammation.- Monitoring Immune Status in Critically Ill Patients.- Tumor Necrosis Factor Receptors in Systemic Inflammation.- Cytokine Neutralization: An Overview.- Immunostimulation with Cytokines in Patients with 'Immunoparalysis'.- Prospects for a Vaccine to Prevent Bacterial Sepsis.

Product details

• Assisted by: Jonathan Cohen (Editor), John C. Marshall (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Paperback / Softback
• Released: 21.01.2002
• EAN: 9783540425892
• ISBN: 978-3-540-42589-2
• No. of pages: 427
• Weight: 610 g
• Illustrations: XIV, 427 p.
• Series: Update in Intensive Care Medicine
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Clinical medicine; B, Care, Medicine, Immunology, Resistance, shock, infectious disease, bacteria, infection, critical care, Intensive / Critical Care Medicine, Intensive Care Medicine, Cytokine, innate immunity, programmed cell death