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Presents a state-of-the-art examination of Crohn's disease (CD), from an historical evolution of the field to future developments of etiopathogenesis, diagnostic evaluation, and therapeutic management. Reviews possible etiologic agents, the various ways CD progresses, novel diagnostic techniques, and standard and innovative therapies. Emphasizes the application of recent advances in basic research to clinical management of the disease.
List of contents
Introduction
Conversation with Burrill B. Crohn, Leon Ginzburg, and Gordon Oppenheimer 63 Years after the Discovery of Crohn's Disease, Henry D. Janowitz
Causes and Mechanisms, Jeffry A. Katz and Claudio Fiocchi
Commentary, Derek Jewell
Epidemiology of Crohn's Disease, Anders Ekbom
Commentary, Robert S. Sandler
Consideration of Smoking in Patients with Crohn's Disease, Bret A. Lashner
Evaluation of the Patient
Pathology and Pathophysiology of Symptoms, William J. Tremaine
Commentary, Sidney F. Phillips
Endoscopic Evaluation, Geert D'Haens and Paul Rutgeerts
The Role of Contrast Barium X-Rays vs. Endoscopy, Burton I. Korelitz
Commentary, Robert Modigliani
Cross-Sectional Imaging in the Evaluation of Crohn's Disease, Richard M. Gore, Gary G. Ghahremani, and Frank H. Miller
Commentary, Daniel Maklansky
Proposed Measures of Disease Activity: How Useful Are They?, Cosimo Prantera and Anna Kohn
Commentary, John W. Singleton
Different Patterns of Crohn's Disease, Lloyd R. Sutherland
Commentary, David B. Sachar
General Therapeutic Approach
Immunosuppressive Therapy of Crohn's Disease: A Historical Perspective, Burton I. Korelitz
Treatment of Active Crohn's Disease with Salazopyrine and Derivatives of Aminosalicylic Acid (5-ASA), Cosimo Prantera, Maria Lia Scribano, and Eva Berto
The Role of Steroids in the Management of Crohn's Disease, Burton I. Korelitz
Clinical Picture of Crohn's Disease: Upper Gastrointestinal Tract, Adrian J. Greenstein and James Aisenberg
Clinical Picture of Crohn's Disease: Lower Intestinal Tract, Norman Sohn
Commentary, John Alexander-Williams
Special Situations
Prevention of Relapse and Recurrence, Cosimo Prantera and Arnaldo Andreoli, Commentary, David B. Sachar
Nutrition and Special Diets, John E. Lennard-Jones
Commentary, Arthur D. Heller
Crohn's Disease in Childhood and Adolescence, Jay A. Barth and Richard J. Grand
Commentary, Frederic Daum
Crohn's Disease in the Elderly, Geetanjali A. Akerkar and Mark A. Peppercorn
Commentary, Nadir Arber and Peter R. Holt
Refractory Crohn's Disease, Stephen B. Hanauer
Commentary, Theodore M. Bayless
The Role of Antibiotics in Crohn's Disease, Peter S. Margolis and Walter R. Thayer, Jr.
Commentary, Cosimo Prantera
Pregnancy and Fertility in Crohn's Disease, Daniel H. Present
Commentary, Robert Burakoff
Psychosocial Issues in Crohn's Disease, Susan Levenstein
Quality of Life Issues in Crohn's Disease, Douglas A. Drossman
Commentary, Barbara S. Kirschner
The Psychiatric Treatment of Patients with Crohn's Disease, Marvin Kaplan
Commentary, Barbara S. Kirschner
Extraintestinal Manifestations, Andrew S. Warner and Richard P. MacDermott
Commentary The Systemic Nature of Inflammatory Bowel Disease, Lloyd Mayer
Liver Complications, Harvey M. Lieberman
Commentary, Nicholas F. LaRusso
Malignancy in Crohn's Disease, Paul M. Choi
Commentary, Burton I. Korelitz
Ileal Pouch in Crohn's Disease, R. John Nicholls
The Effects of Nonsteroidal Anti-Inflammatory Drugs on Crohn's Disease, Joseph B. Felder
Commentary, Burton I. Korelitz
Medical Therapy of Crohn's Disease: Obsolete or Unproven Approaches, Samuel Meyers
The Experience of Crohn's Disease: Is the Bed Now a Table?, Howard M. Spiro
The Future of Crohn's Disease: New Developments in Etiopathogenesis and Therapeutics, Maria T. Abreu and Stephan R. Targan
About the author
Prantera, Cosimo; Korelitz, Burton
