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Zusatztext "The authors of this volume provide an in-depth review of the clinical and pharmacogenomic relevance of biochips! ChIP-chip assays! and high-throughput approaches. ? The book includes coverage of experimental theory! quality control! clinical laboratory sampling considerations! database concepts! industrial laboratory design! and the analysis of the resultant large data sets. ? Written in an easily accessible style! the breadth of coverage introduces the subject to those new to the field! while the depth of coverage forms a foundation for future work." - In Anticancer Research! Vol. 27! No. 3B! May/June 2007"This book is a must have for students who use biochips in their graduate work or others initiating efforts in these areas . . . In summary! Biochips as Pathways to Drug Discovery provides a broad yet detailed look at the use of DNA microarrays in drug discovery." - Matthew D. Disney! The University at Buffalo! The State University of New York! in ChemMedChem! 2008! No. 3 Informationen zum Autor Gary Hardiman Klappentext Providing a comprehensive and real world examination of biochip technologies! this book goes on to explore their applications to drug discovery. The book presents a detailed overview of the current state of biochip technology! examining the effects of biochips on biomedical research and specifically the pharmaceutical industry. This text presents technology platforms in detail and explores the clinical relevance of biochips! ChIP-chip assays! and high-throughput approaches. It also covers intellectual property concerns and includes applications to the study of disease! drug-safety and toxicogenomics! and Pharmacogenomics and SNPs (Single Nucleotide Poymorphisms). Zusammenfassung Explores the tools and skills required at each step of the discovery process when using biochips to determine biological outcomes. This work provides a review of the clinical and pharmacogenomic relevance of biochips, ChIP-chip assays, and high-throughput approaches. Inhaltsverzeichnis 107087845 ...
