Fr. 126.00

Nucleotides and Regulation of Bone Cell Function

English · Hardback

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Informationen zum Autor Geoffrey Burnstock, Timothy R. Arnett Klappentext Written by the pioneers who have energized the research! Nucleotides and Regulation of Bone Cell Function covers many aspects of purinergic signaling with regard to osteoblasts! osteoclasts! and chondrocytes! providing an exploration into how nucleotides act on skeletal cells. It reveals the distribution of receptors for purines and pyrimidines in both neuronal and non-neuronal cells! considers purinergic and P2 nucleotide receptor signaling in osteoclasts! and examines the role of signaling in regulating cartilage metabolism and chondrocyte function. It also considers the pathophysiologic implications of the findings! and discusses the potential of purine-related therapies for a variety of diseases. Zusammenfassung Covers various aspects of purinergic signaling with regard to osteoblasts, osteoclasts, and chondrocytes. This book reveals the distribution of receptors for purines and pyrimidines in both neuronal and non-neuronal cells. It examines the role of signaling in regulating cartilage metabolism and chondrocyte function. Inhaltsverzeichnis Purinergic Signaling in Osteoblasts, P2 Nucleotide Receptor Signaling in Osteoclasts, The Role of Purinergic Signaling in the Interactions between Skeletal Cells, Role of Purine and Pyrimidine Nucleotides and Nucleosides in Regulation of Cartilage Metabolism and Chondrocyte Function, ATP Release Mechanisms, Purinergic Signaling in Inflammation and Immunomodulation, Future Directions, Index

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