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Oral Microbiology At A Glance is the new title in the highly popular at a Glance series. It provides a concise and accessible introduction and revision aid. Following the familiar, easy-to-use at a Glance format, each topic is presented as a double-page spread with key facts accompanied by clear diagrams encapsulating essential information.
Systematically organized and succinctly delivered, Oral Microbiology At A Glance covers:
* Oral microbial origins of health or disease
* Various infections ranging from dental caries, periodontal and endodontic infections to oral mucosal, bone, and systemic infections
* Local and systemic extensions of oral infections
* Sterilization, disinfection, infection control methods, and bioterrorism
Oral Microbiology At A Glance is the ideal companion for students of microbiology, all students of dentistry, and early career clinicians. In addition the text will provide valuable insight for general dental practitioners wanting to update their knowledge of oral microbiology and immunology, as well as dental hygienists, therapists and technicians.
List of contents
About the authors
Preface
1 Introduction to oral microbiology
Commensals and pathogens
Oral diseases
2 In the beginning
The first microbes
Microbial basis of infectious disease
Miller and the chemoparasitic theory of caries
Oral and dental research
3 Caries as an infectious disease
Dental caries as a transmissible disease
Streptococcus mutans
Mutans group streptococci
Link between S. mutans and dental caries
Immunity to caries
4 General properties of saliva
Saliva production
Protective role of saliva
Salivary pellicle
Saliva as a nutrient
5 Salivary mucins and agglutinins
Composition of mucins
Properties of mucins
Bacterial agglutination
6 Secretory Immunoglobulin A
Production of S-IgA
Functions of S-IgA
Inactivation of salivary defenses
Development of S-IgA
The window of infectivity
Selective IgA deficiency
7 Anti-microbial properties of saliva
Anti-microbial components in saliva
8 Innate defences
Anti-microbial peptides (AMPs)
Human AMPs
9 Microbes in the oral cavity
Primary colonizers
Beneficial effects of bacterial colonizers
Ecological plaque hypothesis
Ecology and disease
10 Molecular microbial taxonomy
Molecular taxonomy
Discontinuous gradient gel electrophoresis
DNA chips
11 Systems approaches to oral microbiology
Transcriptomics
Proteomics
Gene ontology
Post-translational networks
Tiled arrays
12 Oral streptococci
The genus Streptococcus
Viridans streptococci
Lancefield grouping
Relatedness and pathogenicity of streptococci
13 Microbial adherence
Adherence
Long-range adherence
Specific adhesion
Oral bacterial adhesins and receptors
14 Complex communities
Inter-microbial reactions
Co-adhesion
Metabolic associations
Antagonism
15 Biofilms
Biofilm development
Microbial recognition of surfaces and interbacterial communication
The biofilm matrix, resilience and resistance
16 Bacterial polysaccharides
Extracellular polysaccharide production
Glycosyltransferases and fructosyltransferases
Glucan binding proteins
EPS produced by oral Gram-negatives
17 Microbiology of caries
Structure of teeth
Dental caries
Types of dental caries
Important bacteria in caries
Emerging and polymicrobial pathogens
18 Virulence factors of S. mutans
Initial attachment to tooth surfaces
Polysaccharide production
Acid production
Acid tolerance
Biofilm adaptation
19 Host and environmental factors in caries
Host factors
Dietary factors
Caries risk assessment
20 Fluoride
Modes of action of fluoride
Strategies for fluoride delivery
Anti-microbial effects of fluoride
Enhancing anti-microbial effects
21 Anti-caries strategies
Inhibitors
Probiotics
Immunization
Vaccination
22 Periodontal diseases
Classification of periodontal diseases
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