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Informationen zum Autor Tadhg P. Begley is Professor of Chemistry and Chemical Biology at Cornell University. Begley (PhD, California Institute of Technology, 1983) is a leading figure in the chemical biology community. He is the recipient of a number of awards for teaching and research, including the Merck Faculty Development Award and the Camille and Henry Dreyfus Teacher-Scholar Award. Klappentext The Wiley Encyclopedia of Chemical Biology is an authoritative new work whose goal is to illuminate the crucial role of chemistry and chemical techniques in the life sciences. The encyclopedia will adopt an inclusive editorial approach, encompassing fundamental and blue-sky science as well as those areas of research that have more immediate medical or commercial applications. The scope and structure of the work will reflect the multidimensional character of chemical biology, focusing in particular on the fundamental science of biological structures and systems, the use of chemical and biological techniques to elucidate that science, and the applications of this knowledge in areas as diverse as drug discovery, sensor technology, and catalysis. Major topics areas covered in the encyclopedia: Chemical Views of Biology Biomolecules within the Cell Chemistry of Biological Processes and Systems Chemical Biology of Cellular Compartments Synthetic Molecules as Tools for Chemical Biology Technologies and Techniques in Chemical Biology Applications of Chemical Biology Zusammenfassung The first encyclopaedic reference work in the important new field of chemical biology, which is crucial for the understanding of cellular processes and the design of new drugs. 300 detailed articles reviewing the state of the art in this field. A distinguished editorial board chaired by Tadhg Begley of Cornell University. Inhaltsverzeichnis ADME properties of drugs. AdoMet-dependent methyltransferases, Chemistry of. Alkaloid Biosynthesis. Allergy and Asthma, Small Molecules to Target. Amino Acids, Chemical Properties of. Aminoacyl tRNA Synthetases, Chemistry of. Amyloid Formation. Antibiotics, Bacterial Resistance to. Antibiotics, Biosynthesis of. Anxiety Disorders, Macromolecular Pathways and Interactions. Apoptosome and Caspase Activation. Artificial Metalloproteins, Design and Engineering of. ATP Synthesis, Chemistry of. Attenuation, Control of Gene Expression by. B12-Dependent Enzyme Reactions, Chemistry of. Bacterial DNA Polymerases, Chemistry of. Bacteriorhodopsin, Chemistry of. Biocatalysis and Biotransformation. Biocatalysts and Chemocatalysts in the Pharmaceutical Industry. Biocompatibility of Materials in Medical Devices. Calcium Pump, Chemistry of. Calcium Signaling. Carbohydrate-Carbohydrate Interactions. Catalytic Antibodies (abzymes), Synthetic. Catalytic Modes in Natural Ribozymes. Cell Cycle, Regulation of. Cell Death, Biological Mechanisms and Small Molecule Inhibitors of. Cell Membranes, Dynamics of. Cellular Energy Metabolism and Integrated Oxidative Phosphorylation. Chaperones, Molecular. Chemical Libraries to Screen for Biologically Active Small Molecules. Chemical Molecules that Regulate Transcription and Facilitate Cell-to-Cell Communication. Chlorophylls and Carotenoids, Chemistry of. Chromosome Formation. Chronic Obstructive Pulmonary Disease (COPD), Mechanisms of. Circular Dichroism for Natural Products. Click Peptides, Design and Applications of. CoA-Dependent Enzymes, Chemistry of. Cofactor Biosynthesis. Collagen Triple Helix, Stability of. Combinatorial Libraries: Overview of Applications in Chemical Biology. Controlled Drug Delivery: Pharmacokinetic Considerations, Methods and Systems. Cyclooxyge...
