Read more
Antibiotic Resistance and Nanotherapy is a comprehensive guide that takes an interdisciplinary approach to address the pressing issue of antibiotic resistance and explores possibility of nanotherapy as a cutting-edge strategy to treat illnesses that are resistant to antibiotics, employing nanoparticles to target and kill bacteria selectively without damaging healthy cells. It details the underlying mechanisms of drug resistance in intracellular and extracellular pathogens and explores the latest advancements in nanotechnology, including the development of innovative nanomaterials and delivery systems that can be utilized to combat antibiotic-resistant infections. The book also tackles the ethical and practical challenges associated with implementing nanotherapy for bacterial resistance. Featuring contributions from experts in the field,
Antibiotic Resistance and Nanotherapy is an essential resource for researchers, medical professionals, and policymakers seeking to understand and tackle the immediate threat posed by antibiotic resistance
List of contents
1. Introduction To Planktonic and Biofilm-Mediated Antimicrobial Resistance and Role of Nanotechnology in Overcoming Biofilm-Mediated Antibiotic Resistance
2. Key Determinants of Antimicrobial Resistance: Exploring the Influence of Antibiotic Pollution on the Emergence of Multidrug-Resistant Microbes
3. Drug Resistance Mechanism in Intracellular Pathogens and Modulation
4. Drug Resistance Mechanism in Extracellular Pathogens and Modulation
5. Metal-based Nanomedicine Against Intracellular Pathogens
6. Polymer-based nanomedicine against intracellular pathogens
7. Lipid-based Nanomedicine Against Intracellular Pathogens
8. Metal-based Nanomedicine Against Extracellular Pathogens
9. Polymer-based Nanomedicine Against Extracellular Pathogens
10. Lipid-based Nanomedicine Against Extracellular Pathogens
11. Interaction Between Infected Host Cells and Nanodelivery Systems
12. Nanoformulations for Local and Targeted Delivery of Antimicrobial Agent and Their Impact on Gut Microbiota
13. Innovative Strategies Utilizing Nanoparticles to Disrupt C-Di-GMP and Quorum Sensing
14. CRISPR-Cas Systems for Antibiotic Resistance
15. Synergistic Effects of Natural Compounds and Repurposed Drugs in Nanotherapy: A Strategy to Combat Biofilm-Associated Infections
16. Safety, Ethical, Regulatory Issues, and Challenges of Nanotherapy for Antimicrobial Resistance
About the author
Dr. Awanish Kumar is currently an Associate Professor and Head of the Department of Biotechnology at the National Institute of Technology, Raipur (CG), India. He has more than 16 years of research experience. He received his PhD in Biotechnology from the CSIR-Central Drug Research Institute, Lucknow, India, and Jawaharlal Nehru University, Delhi, India, and completed his postdoctoral studies at McGill University, Montreal, Canada. His research interests are infection biology, drug targeting, and drug discovery. He has served on various national and international organizations in different academic and research capacities. He has also served on many national committees and scientific advisory panels, as a member of many international professional research societies, and as a reviewer and editorial board member of reputed and refereed journals. He has authored or edited several monographs, books, and book chapters.
Dr. Sharda Bharti currently an Assistant Professor in the Department of Biotechnology at the National Institute of Technology (NIT), Raipur, India, an institute of national Importance under the Ministry of Education-Government of India. She completed her M. Tech and Ph.D. in Environmental Science and Engineering from the Indian Institute of Technology (IIT) Bombay, Mumbai, India. Her research interests primarily focus on the application of nanomaterials in water disinfection, water and wastewater treatment, antimicrobial resistance, and environmental health and safety. She has more than three years of experience in teaching and in industry. She also serves as reviewer for several reputed journals: Applied Nanoscience, The Institute of Engineers: Series A, Heliyon, Arabian Journal of Chemistry and a few others. She has more than 15 publications in different reputable international journals and conference papers, several book chapters in books of international repute, and has presented papers at several national and international conferences.
