Handbook of Nutraceuticals - Science, Technology and Engineering

This book explores the complete development cycle of nutraceuticals and nano-nutraceuticals, with particular focus on manufacturing techniques and formulation strategies. It discusses their physicochemical behavior and presents innovative analytical characterization methods. The text also includes a variety of formulation approaches along with pharmacologic and pharmacokinetic evaluations. Several chapters address the controlled delivery of nutraceutical components, and the use of natural and biodegradable polymers in delivery systems is thoroughly reviewed. In vitro evaluation techniques for assessing nutrient delivery effectiveness are covered in detail, along with discussions on bioavailability, food additives, and encapsulation technologies. A dedicated chapter on the future of controlled-release technologies rounds out the volume.

List of contents

Part I: Nutraceuticals and nano nutraceuticals -Formulation and Characterisation.- Nutraceuticals and nano nutraceuticals-overview of the market.- Potential nutraceutical ingredients.- Nutrient Requirements in health and disease. Nutraceutical and nano nutraceuticals for different class of diseases: CNS and Alzheimer's disease. Nutraceuticals and nano nutraceuticals formulations for CVS and BP.- Nutraceuticals and nano nutraceuticals formulations for obesity, diabetes and kidney disease. Nutraceuticals and nano nutraceuticals formulations for rheumatoid and osteoarthritis. Nutraceuticals and nano nutraceuticals formulations for gastrointestinal disorders. Nutraceuticals and nano nutraceuticals formulations for chronic disease-cancer.- Nutraceuticals and nano nutraceuticals formulations for inflammation and wound healing. Solutions, aqueous solutions, juices and syrups and its evaluation.- Emulsions, Suspensions and evaluation of nutraceuticals and nano nutraceuticals formulations.- Solid dosage forms  and evaluation of nutraceuticals and nano nutraceuticals formulations.- Microscopical methods for evaluating the nutraceuticals and nano nutraceuticals formulations.- Spectroscopical methods for evaluating the nutraceuticals and nano nutraceuticals formulations.- Chromatographic techniques for evaluating the nutraceuticals and nano nutraceuticals formulations.- Microbiological evaluation of the nutraceuticals and nano nutraceuticals formulations.- Stability and thermal analysis for evaluating the nutraceuticals and nano nutraceuticals formulations.- Part II: Controlled and Sustained Delivery of Nutraceuticals and Nano Nutraceuticals.- General overview of controlled and sustained release systems - Its release mechanism and kinetics.- Food derived biopolymers for delivery of nutrients.- Biodegradable synthetic polymers for delivery of nutrients.- Lipid, Self-assembly of lipid particles  and Liposomes delivery of nutritional components.- Micro emulsion, nano emulsion and Emulsion droplet system for delivering bioactive component.- Hydrogels and Organogels for delivering bioactive component.- Nanoencapsulation of controlled release of active components.- Fluidized bed drying, freeze drying and pan coating process of bioactive ingredient.- Spray drying, Spray chilling and spray cooling of nutraceutical ingredient.- Hot melt extrusion and complex coacervation system for delivering bioactive component.- Ionotropic gelation and polyelectrolyte complexation technique for delivering active components.- Interfacial and in-situ polymerization system for delivering bioactives.- Sol-gel, phase inversion precipitation and microfluidic system for controlled delivery of bioactives.- Granulation, electrodynamic atomization and supercritical fluid technology for delivering bioactive components.- Electrospinning technology for controlled delivery of bioactive ingredient.- Assessing the bioavailability and testing the effectiveness of nutraceuticals and nano nutraceuticals.- Future outlook of controlled release delivery technologies for nutraceuticals and nano nutraceuticals.

About the author

Dr. R. Rajakumari is currently working in the Department of Pharmaceutics at The Oxford College of Pharmacy, Bengaluru. She holds a PhD in Pharmaceutics (Nanoscience and Nanotechnology) from Mahatma Gandhi University, Kottayam. She has authored several research articles, book chapters and edited volumes in the areas of nanomedicine, food science and nutraceuticals and patent. Her research interests include nanotechnology-based drug delivery, biomaterials, development of innovative nutraceutical and pharmaceutical formulations and polymer chemistry. Dr Rajakumari has received research grants and has actively participated in presenting and organizing several national and international conferences.
 
Prof. (Dr.) Sabu Thomas is an eminent scientist and academic leader in polymer science and nanotechnology. A former Vice-Chancellor of Mahatma Gandhi University, he currently serves as Chairman of the Trivandrum Engineering Science and Technology Research Park (TrEST) and Director of the School of Energy Materials and the International Centre for Nanoscience and Nanotechnology. He also serves as Director of the Department of Physics and Electronics at CHRIST (Deemed-to-be University) and is associated with leading international institutions, including Chulalongkorn University in Thailand and the University of Johannesburg in South Africa. With over three decades of teaching and research experience, Prof. Thomas has supervised numerous Ph.D. scholars, published extensively, and holds multiple patents. He has received national and international research grants that have advanced interdisciplinary work in advanced materials, nanotechnology, and polymer science. Prof. Thomas has been honored with prestigious awards and honorary doctorates, reflecting his global impact on scientific research and education.

Summary

This book explores the complete development cycle of nutraceuticals and nano-nutraceuticals, with particular focus on manufacturing techniques and formulation strategies. It discusses their physicochemical behavior and presents innovative analytical characterization methods. The text also includes a variety of formulation approaches along with pharmacologic and pharmacokinetic evaluations. Several chapters address the controlled delivery of nutraceutical components, and the use of natural and biodegradable polymers in delivery systems is thoroughly reviewed. In vitro evaluation techniques for assessing nutrient delivery effectiveness are covered in detail, along with discussions on bioavailability, food additives, and encapsulation technologies. A dedicated chapter on the future of controlled-release technologies rounds out the volume.

Product details

• Assisted by: R Rajakumari (Editor), R. Rajakumari (Editor), Thomas (Editor), Sabu Thomas (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Hardback
• Released: 18.07.2026
• EAN: 9783031987908
• ISBN: 978-3-0-3198790-8
• No. of pages: 1200
• Illustrations: XXX, 1200 p. 181 illus., 158 illus. in color.
• Subjects: Natural sciences, medicine, IT, technology > Technology > Mechanical engineering, production engineering; Lebensmittel- und Getränketechnologie, Medizinische Spezialgebiete, Biopolymers, Nutraceuticals, food nanotechnology, controlled release, sustained release, Nanomedicine and Nanotoxicology, Bioactives, Nano Nutraceuticals, Dietary Ingredient