Dental Gold Alloys and Gold Nanoparticles for Biomedical Applications - DE

This book focuses on recent advances in dental gold alloys and gold nanoparticles (GNPs) for biomedical applications. Dental gold alloys combine several highly desirable mechanical properties, such as high strength, ductility, and elasticity, with extremely robust chemical stability in the mouth, known as high biocompatibility. The new edition presents advanced dental gold alloys for fixed dentures, evaluating the influence of individual elements on the mechanical and other characteristics of the alloys.
In the section on the use of GNPs as novel gold biomaterials that provide a multifunctional platform for cellular imaging, biosensing, and targeted drug delivery in tumor immunotherapy and photothermal therapy, their application for incorporation into creams and for rapid LFIA tests is demonstrated.
Starting with a comprehensive review of the development and application of dental gold alloys, the book discusses the properties of materials that are crucial for dental applications, focusing on aspects such as microstructure, mechanical properties, chemical and corrosion stability, aging, biocompatibility, and color stability. The book then focuses on the use of GNPs in dental applications, delving into various GNP synthesis techniques to specifically tailor size, shape, and stability in biological media. The new supplement presents the scientific knowledge for the use of GNPs in creams and the studies needed to evaluate their safe use. The fact is that the characterization and safety assessment of nanoparticles and other nanomaterials in cosmetics is very challenging. Cosmetic creams are complex media with multiple components that can affect the physical and chemical properties of nanomaterials, alter their behavior and complicate the transfer of their toxicological aspects to different cosmetic formulations.
In addition to these factors, it discusses how their route of exposure, surface chemistry, and how steric effects of their coating affect the biodistribution and determine the level of toxicity of GNPs in the human body. The final section presents the global manufacturers of GNPs and the characteristics of their products. This book contains reviews of the current literature and updated published experimental results and offers an attractive resource for practicing scientists and engineers working in the field of various types of gold-based biomaterials.

List of contents

Introduction.- Dental Gold Alloys.- Gold Nanoparticles.

About the author

Prof. Dr. Rebeka Rudolf after graduation from the Faculty of Mechanical Engineering in the University of Maribor, Slovenia, continued with postgraduate studies (master’s degree in 1997) up to a Doctorate in 2002. She has been employed permanently at the University since 1993. In 2006, she was additionally employed by Zlatarna Celje d.o.o. as Research Manager and as Leader of the Research Group. In 2017, she achieved the level of Research Counsellor and in 2023 Full position of Professor in the University of Maribor within habilitation field: Materials. At the end of 2023, she was additionally employed by Pomurje Science and Innovation Center, Murska Sobota as Research Councillor. She has focused intensively on the development of new gold dental alloys, studying their biocompatibility and corrosion resistance, which are the applicable values for the field of dentistry. She has published 312 units in co-authorship in the last 5 years in the fields of materials, dental alloys and nanotechnology: 67 scientific papers, 36 professional articles, 209 collected works (mentoring and co-mentoring) and conference proceedings.  
Prof. Dr. Vojkan Lazić is Full Professor and Dean at the School of Dental Medicine at the University of Belgrade. After graduation from the School of Dental Medicine in Belgrade in 1991, he continued with a Master of Science Degree in 1998 to a Doctorate in 2003. He has been employed at the University permanently since 1994. Since then, he has been involved in teaching and research, especially in dental materials. The main research is in the field of new dental alloys for ceramic fused to metal restorations, acrylic resin with nanoparticles for complete or partial dentures and silicones for epitheses. He was Participant and Main Researcher in six scientific projects, mainly in dental materials. In July 2008, he was visiting Professor at the Advanced Prosthodontic Division at UCLA, CA—USA. Until now, he has published 52 papers, of which 45 were scientific papers, then 110 reports at international and domestic conferences and six books, of which he co-authored in three textbooks. So far, he has been Mentor in six completed Doctoral Dissertations.
Prof. Dr. Vojkan Lazić is Full Professor and Dean at the School of Dental Medicine at the University of Belgrade. After graduation from the School of Dental Medicine in Belgrade in 1991, he continued with a Master of Science Degree in 1998 to a Doctorate in 2003. He has been employed at the University permanently since 1994. Since then, he has been involved in teaching and research, especially in dental materials. The main research is in the field of new dental alloys for ceramic fused to metal restorations, acrylic resin with nanoparticles for complete or partial dentures and silicones for epitheses. He was Participant and Main Researcher in six scientific projects, mainly in dental materials. In July 2008, he was visiting Professor at the Advanced Prosthodontic Division at UCLA, CA—USA. Until now, he has published 52 papers, of which 45 were scientific papers, then 110 reports at international and domestic conferences and six books, of which he co-authored in three textbooks. So far, he has been Mentor in six completed Doctoral Dissertations.
Prof. Dr. Vojkan Lazić is Full Professor and Dean at the School of Dental Medicine at the University of Belgrade. After graduation from the School of Dental Medicine in Belgrade in 1991, he continued with a Master of Science Degree in 1998 to a Doctorate in 2003. He has been employed at the University permanently since 1994. Since then, he has been involved in teaching and research, especially in dental materials. The main research is in the field of new dental alloys for ceramic fused to metal restorations, acrylic resin with nanoparticles for complete or partial dentures and silicones for epitheses. He was Participant and Main Researcher in six scientific projects, mainly in dental materials. In July 2008, he was visiting Professor at the Advanced Prosthodontic Division at UCLA, CA—USA. Until now, he has published 52 papers, of which 45 were scientific papers, then 110 reports at international and domestic conferences and six books, of which he co-authored in three textbooks. So far, he has been Mentor in six completed Doctoral Dissertations.
Dr. Karlo T. Raić is a Professor Emeritus at the Department of Metallurgical Engineering (DME), Faculty of Technology and Metallurgy, University of Belgrade, Serbia (FTM-UB-Ser). His teachings span a broad range of courses, including Transport Phenomena in Materials Engineering, Surface Engineering, Metallic Materials in Medicine, and Iron and Steel-selected Topics. Actively involved in academic and research communities, Professor Raić has participated in and coordinated numerous national and international projects. Additionally, he has provided invaluable mentorship as a thesis advisor and served on various organizing committees. As a reviewer for international and national journals, monographs, conference papers, and grant applications, his expertise has guided the advancement of new materials and technologies. His influence extends further as a dedicated member and leader of international and national conference committees.
 

Summary

This book focuses on recent advances in dental gold alloys and gold nanoparticles (GNPs) for biomedical applications. Dental gold alloys combine several highly desirable mechanical properties, such as high strength, ductility, and elasticity, with extremely robust chemical stability in the mouth, known as high biocompatibility. The new edition presents advanced dental gold alloys for fixed dentures, evaluating the influence of individual elements on the mechanical and other characteristics of the alloys.
In the section on the use of GNPs as novel gold biomaterials that provide a multifunctional platform for cellular imaging, biosensing, and targeted drug delivery in tumor immunotherapy and photothermal therapy, their application for incorporation into creams and for rapid LFIA tests is demonstrated.
Starting with a comprehensive review of the development and application of dental gold alloys, the book discusses the properties of materials that are crucial for dental applications, focusing on aspects such as microstructure, mechanical properties, chemical and corrosion stability, aging, biocompatibility, and color stability. The book then focuses on the use of GNPs in dental applications, delving into various GNP synthesis techniques to specifically tailor size, shape, and stability in biological media. The new supplement presents the scientific knowledge for the use of GNPs in creams and the studies needed to evaluate their safe use. The fact is that the characterization and safety assessment of nanoparticles and other nanomaterials in cosmetics is very challenging. Cosmetic creams are complex media with multiple components that can affect the physical and chemical properties of nanomaterials, alter their behavior and complicate the transfer of their toxicological aspects to different cosmetic formulations.
In addition to these factors, it discusses how their route of exposure, surface chemistry, and how steric effects of their coating affect the biodistribution and determine the level of toxicity of GNPs in the human body. The final section presents the global manufacturers of GNPs and the characteristics of their products. This book contains reviews of the current literature and updated published experimental results and offers an attractive resource for practicing scientists and engineers working in the field of various types of gold-based biomaterials.

Product details

• Authors: Andrej Ivanic, Andrej Ivanič, Vojkan Lazic, Vojkan Lazić, Peter Majeric, Peter et al Majeric, Peter Majerič, Karlo T. Raic, Karlo T. Raić, Rebeka Rudolf
• Publisher: Springer, Berlin
• Languages: English
• Product format: Hardback
• Release: 25.11.2025
• EAN: 9783031986376
• ISBN: 978-3-0-3198637-6
• No. of pages: 160
• Illustrations: Approx. 160 p.
• Series: Springer Series in Materials Science
• Subjects: Natural sciences, medicine, IT, technology > Technology > Mechanical engineering, production engineering; Chemie, Werkstoffprüfung, ZAHNHEILKUNDE, Technische Anwendung von Biomaterialien, dentistry, Metals and Alloys, Biomaterials, Tensile test, Materials Characterization Technique, transmission electron microscopy, Nanoparticle Synthesis, Fromation Mechanisms, Synthesis of Nanoparticles, Mechanical Properties of Gold Alloys, Gold Biomaterials, Surface Chemistry of Nanoparticles, Thermomechanical Treatment of Dental Alloys, Ultrasonic Spray Pyrolysis, Gold Nanoparticles, Biocompatibility and Corrosion