Probiogenomics and Probiomics - Concepts, Techniques, Applications, and Achievements

Probiogenomics and Probiomics: Concepts, Techniques, Applications, and Achievements is a pioneering reference book that marks a significant milestone in the emerging fields of probiogenomics and probiomics. As the first comprehensive resource in these disciplines, the book offers a detailed exploration of how genetic insights and omics technologies are revolutionizing our understanding of probiotics and their application in health and disease. Spanning three detailed sections, the book begins by grounding readers in the fundamental concepts of probiotics, including their roles in health enhancement and disease prevention. It progresses into a deep dive into advanced genomic and post-genomic technologies, revealing how these tools are used to dissect and harness the health-promoting capacities of probiotics. From the structure and function of probiotic genomes to the cutting-edge applications in synthetic biology and multi-omics, the book encapsulates the latest advancements and methodologies in the field. The final sections focus on the practical and clinical applications of these microbial marvels, discussing their impact on healthcare, biotechnology, and therapeutics. Whether it's developing new biotechnological products or enhancing therapeutic efficacy, this book covers a broad spectrum of applications, making it an invaluable resource for undergraduate and postgraduate students, researchers, clinicians, and industry professionals involved in drug and probiotics development. With contributions from over ten global experts, "Probiogenomics and Probiomics" not only educates but also inspires, providing a thorough understanding of modern probiogenomics and its potential to shape the future of personalized medicine and healthcare.

List of contents

SECTION I: CONCEPT OF PROBIOTICS
1. Probiotics in health promotion
2. Inhibition/competition of probiotics against pathogenic bacteria
3. Important criteria for choosing probiotics
4. Bugs as drug
5. Safety of probiotics

SECTION II: PROBIOTICS, PREBIOTIC, POSTBIOTICS, AND SYNBIOTICS
6. Probiotics or Prebiotics or Postbiotics which is best? Types, mechanisms, functions, and health promotion applications
7. Synbiotics: mechanisms, functions, benefits, and commercial products
8. Per-clinical (in vitro, in vivo) and Clinical (human) studies and outcomes on probiotics, prebiotics, postbiotics, and synbiotics

SECTION III: PROBIOGENOMICS AND PROBIOMICS
9. Classical and next-generation approaches in probiotics: advantages and disadvantages
10. Genomic and metagenomic approaches and applications in Probiogenomics
11. Genome reconstruction and applications in probiogenomics
12. Structure and function of probiotic bacterial genomes compared to non-probiotic bacteria
13. Genome evolution and interactions in probiogenomics
14. Transcriptomics approaches in probiomics: applications and achievements
15. Proteomics approaches in probiomics: applications and achievements
16. Metabolomics approaches in probiomics: applications and achievements
17. Phenomics approaches in probiomics: applications and achievements
18. Multi-omics approaches in probiotics
19. Synthetic biology and engineering for probiotics
20. Applications of probiomics in development of new products in biotechnology, healthcare, and therapeutics
21. Next-generation Probiotics
22. Precibiomics: the precision health approaches with probiotics
23. Bioinformatics and computational approaches in preobiogenomics and probiomics
24. Recent technological advances in preobiogenomics and probiomics

About the author

Dr. Debmalya Barh is currently a Visiting Full Professor (Titular, Grade-E) in Bioinformatics and Precision Health at the Department of Genetics, Ecology, and Evolution, ICB, Federal University of Minas Gerais, Brazil and honorary scientist of the Institute of Integrative Omics and Applied Biotechnology (IIOAB), India. With over 20 years of experience, he has led academic, healthcare, molecular diagnostic, and bioinformatics industry endeavors. He works with more than 400 scientists from 100+ top ranked organizations across 40+ countries and has 220+ publications and a branded editor for 10+ cutting-edge omics related reference books. He is an expert in in precision/personalized health and integrative omics-based biomarker and target discovery in infectious and complex lifestyle diseases.Prof. Vasco Azevedo is a senior professor of the Department of Genetics, Ecology, and Evolution at the Federal University of Minas Gerais, Brazil. He is a member of the Brazilian Academy of Science and Knight of the National Order of Scientific Merit of the Brazilian Ministry of Science, Technology, and Innovation. He is also a research 1A of the National Council for Scientific and Technological Development (CNPq), which is the highest position. His total research publications include more than 500 research articles, nine books, and more than 52 book chapters. Professor Azevedo is a pioneer of the genetics of lactic acid bacteria, Probiotics, and Corynebacterium genomics in Brazil. He has specialized and currently researching bacterial genetics, genomes, transcriptomes, and proteomes for the development of new vaccines and diagnostic against infectious and autoimmune diseases.

Product details

• Assisted by: Barh Debmalya (Editor), Vasco Ariston De Carvalho Azevedo (Editor)
• Publisher: Elsevier
• Languages: English
• Release: 12.01.2026
• EAN: 9780443404733
• ISBN: 978-0-443-40473-3
• Subjects: Natural sciences, medicine, IT, technology > Biology > Genetics, genetic engineering; SCIENCE / Life Sciences / Genetics & Genomics, Genetics (non-medical), Dna & Genome