The Immunology of the Pig

The Immunology of the Pig is a comprehensive and detailed exploration of the immune systems of domestic pigs, offering an invaluable resource for researchers, veterinarians, and students in the fields of immunology, veterinary medicine, and biomedical science. This text covers both the innate and adaptive immune systems of pigs, highlighting the unique features that make them an excellent model for human immune system studies. By examining the applied immunity of pigs, including available vaccines and immune-mediated diseases, this book addresses a critical need for understanding porcine immunology in both agricultural and biomedical contexts. The book is meticulously structured to cover a wide range of topics. It begins with the evolutionary origins and domestication of pigs, providing a historical context that enriches the understanding of their immune systems. Subsequent chapters explore key aspects of porcine immunology, including piglet ontogeny, reproduction, and lactation; innate immunity; hematology; cytokine functions; antigen processing cells; and lymphoid organs. Detailed discussions on the major histocompatibility complex, innate lymphoid cells, B and T cell systems, and immunity on body surfaces offer a thorough insight into the complex mechanisms at play. Additionally, the text addresses the microbiota's role, vaccination strategies, and immunity to various bacterial, viral, and parasitic diseases, rounding out a holistic view of porcine immune health.

The Immunology of the Pig is an essential reference for anyone involved in veterinary science, immunology, or biomedical research. It provides a deep dive into the pig's immune system, presenting a wealth of information that is both scientifically rigorous and practically applicable. By understanding the parallels between porcine and human immune systems, researchers can leverage this knowledge to advance medical science, particularly in the areas of xenotransplantation and disease modeling. This book is a vital tool for advancing our understanding of immunology and improving health outcomes for both pigs and humans.

List of contents

1. The Evolution and Domestication of the Pig
2. Piglet Ontogeny, Reproduction, and Lactation
3. Innate Immunity in the Pig
4. The Hematology of the Pig
5. The Porcine Sickness Response
6. Porcine Cytokines
7. Antigen Processing Cells
8. The Lymphoid Organs of the Pig
9. SLA -The Porcine Major Histocompatibility Complex
10. Porcine Innate Lymphoid Cells
11. The Porcine B Cell System
12. The Porcine T Cell System
13. Immunity on Pig Body Surfaces
14. The Microbiota and the Pig Immune System
15. Porcine Vaccines and Vaccination
16. Immunity to Selected Bacterial Diseases of Pigs
17. Immunity to Selected Viral Diseases of Pigs
18. Immunity to Selected Porcine Parasites
19. Porcine Anaphylaxis and Allergic Diseases
20. Immune Complex and Other Hypersensitivity Diseases
21. Porcine Autoimmune Diseases
22. Porcine Immunodeficiency Diseases
23. Pigs and Human Xenografts
24. Pig models of Human Cancers

About the author

Ian R. Tizard, BVMS, BSc, PhD, DSc (Hons), DACVM, is a Diplomate of the American College of Veterinary Microbiologists and a University Distinguished Professor Emeritus of Immunology, Department of Veterinary Pathobiology, The Texas Veterinary Medical Center at Texas A &M University (TAMU), College Station, Texas, USA. Dr. Tizard earned his Bachelor of Veterinary Medicine and Surgery from the University of Edinburgh, Scotland, in 1965. He then completed a Bachelor of Science in Pathology and a PhD in Immunology. After completing his studies, Dr. Tizard became a Post-Doctoral Fellow at the University of Guelph, where he remained as a professor until 1982 when he moved to TAMU. Dr. Tizard wrote the first standardized textbook on Veterinary Immunology in 1977. This text, now in its 11th edition, is used worldwide, and has played a major role in establishing Immunology among the key disciplines.

Product details

• Authors: Ian R. Tizard
• Publisher: Elsevier
• Languages: English
• Product format: Paperback / Softback
• Release: 01.11.2025
• EAN: 9780443415357
• ISBN: 978-0-443-41535-7
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Clinical medicine; Immunology, MEDICAL / Immunology