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This five-volume series provides clinicians with a detailed, up-to-date, well-referenced overview of the latest developments in this rapidly expanding feld. It serves as an
authoritative guide to the diagnosis and treatment of platelet disorders.The primary audience for the series is clinicians, residents and fellows in internal medicine,
cardiology and haematology, as well as clinicians (e.g. neurologists, nephrologists, rheumatologists) and basic scientists who may be concerned with disorders and
cellular mechanisms involving platelets.
List of contents
Chapter 31: Platelet adhesion.- Chapter 32: Platelet shape change.- Chapter 33: Platelets and clot retraction.- Chapter 34: Platelet migration.- Chapter 35: Platelet secretion.- Chapter 36: Platelets and immunity.- Chapter 37: Platelet endothelium interactions.- Chapter 38: Platelets and endothelial permeability.- Chapter 39: Platelets and angiogenesis.- Chapter 40: Platelet interactions with the vessel wall: the kinetics of hemostatic plug formation.- Chapter 41: Platelet-leukocyte interactions.- Chapter 42: Platelet-red blood cell interactions.- Chapter 43: Platelet derived extracellular vescicles.- Chapter 44: Platelets and coagulation.- Chapter 45: Platelets and fibrinolysis.- Chapter 46: Platelet-derived thromboprotective agents.- Chapter 47: Platelets in the newborn.- Chapter 48: Platelets ageing.- Chapter 49: Platelet function tests.- Chapter 50: Platelet counting and platelet dimension measurements.- Chapter 51: Flow-cytometry.- Chapter 52: Platelet aggregation measurement methods.- Chapter 53: Methods for the study of platelet secretion.- Chapter 54: Methods for study of platelet function in (patho)physiologic flow fields.- Chapter 55: In vivo platelet imaging.- Chapter 56: The Role of Artificial Intelligence and Computational Methods in Enhancing the Study of Platelet Biology.- Chapter 57: New approaches and new tools to study platelet function.- Chapter 58: High-throughput multiparametric platelet function testing.- Chapter 59: NGS study of educated platelets for tumor diagnosis.
About the author
Prof. Paolo Gresele, MD, PhD, is Professor of Internal Medicine at the Department of Medicine and Surgery of the University of Perugia, Italy. His research interests are mainly focused on hemostatic and thrombotic disorders, with special attention on the role of platelets in hemorrhagic, cardiovascular and inflammatory diseases. He has been President of Italian Society on Hemostasis and Thrombosis, former chair of the Platelet Physiology Scientific and Standardization Committee of the International Society of Thrombosis and Haemostasis (ISTH) he is member of the panel of experts on ClinGen Hemostasis/Thrombosis Clinical Domain Working Group and is the current Chair of the Specialized Working Group (SWG) on Thrombocytopenias and Platelet Function Disorders of the European Hematology Association (EHA-SWG).
Dr. José A. López, MD has held academic positions at the University of California, San Francisco and Gladstone Institute for Cardiovascular Disease, at the Baylor College of Medicine in Houston, Texas, and, most recently, at the University of Washington, where he holds the title of Professor of Medicine (Hematology) and Adjunct Professor of Biochemistry and Mechanical Engineering. Dr. López is also Chief Scientific Officer of Bloodworks Northwest, a large regional blood center, and directs the Bloodworks Research Institute, where he also runs an active laboratory.
Dr. López is currently serving as Co-Director of the Translational Research Training in Hematology Program, an international program to assist in fellow-to-faculty transition cosponsored by the European Hematology Association and the American Society of Hematology.
Prof. Dominick J. Angiolillo, MD, PhD. is a Distinguished Professor of Medicine with Tenure status, Chief of Cardiology and Medical Director of the University of Florida Health Cardiovascular Center. He is also the Medical Director of Cardiovascular Research, Program Director of the ACGME-accredited Interventional Cardiology Fellowship program, and Staff Cardiologist and Interventional Cardiologist at the University of Florida Health System. Much of Prof. Angiolillo’s professional career has been devoted to interventional cardiology and management of patients with acute coronary syndrome. His largest national and international recognition has been for his pivotal contributions in the field of thrombosis, being a key investigator in the clinical development of numerous novel antithrombotic agents for which he has received numerous national and international academic recognitions.
Professor Clive Page, OBE, BSc, PhD, FRSB, FBPhs (Hon), FFPM (Hon) is an Emeritus Professor of Pharmacology, King’s College London. His main research interests are in the pharmacology of inflammation and respiratory disease. Clive was the co-founder and previous Chairman of the Board of Verona Pharma plc, a NASDAQ listed Company and was instrumental in the discovery and development of Ensifentrine for the treatment of COPD and other respiratory diseases which was recently approved by the FDA. Clive is a recent past President of the British Pharmacological Society and was awarded the Sandoz Prize from the British Pharmacological Society in 1988, The Tanabe Young Investigators Prize from the American College of Clinical Pharmacology in 1996 and the Royal Society of Biology President’s Medal in 2012 for “Outstanding Contributions to the Life Sciences”.
Summary
This five-volume series provides clinicians with a detailed, up-to-date, well-referenced overview of the latest developments in this rapidly expanding feld. It serves as an
authoritative guide to the diagnosis and treatment of platelet disorders.The primary audience for the series is clinicians, residents and fellows in internal medicine,
cardiology and haematology, as well as clinicians (e.g. neurologists, nephrologists, rheumatologists) and basic scientists who may be concerned with disorders and
cellular mechanisms involving platelets.