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This book presents cutting-edge insights into formaldehyde, with a particular focus on endogenous formaldehyde, revealing its many key roles in the human body. It delves into the relationship between endogenous formaldehyde and cognition, as well as age-related cognitive impairment. It discusses different aspects such as formaldehyde metabolism, its function in the brain, links with epigenetics and neurophysiology, and epidemiological and clinical investigations. The author also provides suggestions on how to prevent cognitive impairment caused by excessive endogenous formaldehyde. This book appeals to all readers who are interested in cognitive science and toxicology.
This updated edition significantly expands upon the 1st edition. The author adds five new chapters to broaden and deepen the progression and knowledge of formaldehyde and cognition in recent years.
List of contents
Chapter 1. Formaldehyde from Environment.- Chapter 2. Metabolism of Formaldehyde In Vivo.- Chapter 3. Formaldehyde and Catecholamine Neurotransmitters in Cognitive Impairment.- Chapter 4. Formaldehyde Serves as a Key Factor in the (De)methylation for Memory Formation.- Chapter 5. Dehydration, Formaldehyde, and Age-Related Cognitive Impairment.- Chapter 6. The Role of Formaldehyde in Cell Proliferation and Death.- Chapter 7. Gut Microbiota, Formaldehyde Dysmetabolism, and Cognitive Impairment.- Chapter 8. Multi-functional Protein Tau Aggregation and Cytotoxicity.- Chapter 9. Cognitive Ability and Impairment Related to Formaldehyde.- Chapter 10. Amyloid Deposition, Tau Phosphorylation, ApoE4 Dysfunction and Formaldehyde.- Chapter 11. Formaldehyde Exposure Leads to Circadian Rhythm, Anxiety, Depression, and Other Neuropsychiatric Disorders.- Chapter 12. Formaldehyde, Neuroinflammation and Cognitive Impairment.- Chapter 13. Formaldehyde in Stroke and Vascular Dementia.- Chapter 14. Formaldehyde in Diabetes and Cognitive Impairment.- Chapter 15. Formaldehyde Affects Lifespan and Stress Resistance in Drosophila.- Chapter 16. Molecular, Cellular, and Animal Experiments in Formaldehyde Study.- Chapter 17. Methods in Determination of Formaldehyde.- Chapter 18. Potential Drug Interventions on Formaldehyde Induced Neuronal Toxicity.
About the author
Dr. Rongqiao He is a professor at the State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences. He currently serves as an editor-in-chief for Progress in Biochemistry and Biophysics. From 2007 to 2021, he held the role of editor-in-chief in Microbiology China and now he is the advisor of Microbiology China. In addition, Dr. He is a dedicated editorial board member for Biochimica Biophysica Acta-GS and Science China Life Sciences. Dr. He’s research focuses on the relationship between the structure and function of neuronal proteins, protein chemical modification, misfolding, and neurodegeneration.
Summary
This book presents cutting-edge insights into formaldehyde, with a particular focus on endogenous formaldehyde, revealing its many key roles in the human body. It delves into the relationship between endogenous formaldehyde and cognition, as well as age-related cognitive impairment. It discusses different aspects such as formaldehyde metabolism, its function in the brain, links with epigenetics and neurophysiology, and epidemiological and clinical investigations. The author also provides suggestions on how to prevent cognitive impairment caused by excessive endogenous formaldehyde. This book appeals to all readers who are interested in cognitive science and toxicology.
This updated edition significantly expands upon the 1st edition. The author adds five new chapters to broaden and deepen the progression and knowledge of formaldehyde and cognition in recent years.
