Overall Account of Surface Enhanced Raman Spectroscopy

This book covers all the aspects of surface enhanced Raman Spectroscopy (SERS) including brief history of the discovery of SERS and development of the field, basic principles and enhancement mechanism of SERS.

List of contents

Chapter 1. A brief history of the discovery and development of surface enhanced Raman scattering. 1.1 Introduction. 1.2 Discovery and development. 1.3 Multidisciplinary and interdisciplinary nature of SERS effect. 1.4 Other variants of SERS. 1.5 Signal reproducibility issue. 1.6 Conclusion. References. Chapter 2. Basic principle and enhancement mechanisms for SERS. 2.1 Role of plasmonic nanostructures in SERS. 2.2 Electromagnetic enhancement mechanism. 2.3 Chemical enhancement mechanism. 2.4 Enhancement factor. 2.5 Selection rule. 2.6 Conclusion. References. Chapter 3. Plasmonic nanomaterials: First generation SERS substrates. 3.1 Introduction. 3.2 Plasmonic nanoparticles and colloids. 3.3 Plasmonic thin films. 3.4 Plasmonic 3D materials. 3.5 Conclusions. References. Chapter 4. Plasmonic nanostructures with electromagnetic hot spots: Second generation SERS substrates. 4.1 Introduction. 4.2 Controlled aggregation of colloidal nanoparticles. 4.3 Plasmonic nanorod, nanostar, triangle, nanoshell and other anisotropic shapes. 4.4 Plasmonic nanoparticle dimers and oligomers. 4.5 2D array and 3D superlattice. 4.6 Conclusions. References. Chapter 5. Plasmonic hot spot engineering: Third generation SERS substrates. 5.1 Introduction. 5.2 Individual plasmonic nanoparticle on a flat metal film as SERS substrates. 5.3 Plasmonic nanoparticles with an ultrathin shell as universal SERS substrates. 5.4 Plasmonic tip-enhanced SERS. 5.5 Graphene-enhanced SERS. 5.6 Piezoelectric material-based SERS enhancement. 5.7 Pyroelectric/thermoelectric material-based SERS enhancement. 5.8 Superhydrophobic platform-based SERS enhancement. 5.9 Conclusion. References. Chapter 6. SERS-based detection platforms and signal reproducibility issues. 6.1 Introduction. 6.2 Instrumentation. 6.3 SERS detection platforms. 6.4 Raman probe. 6.5 Origin of poor signal reproducibility and possible solutions. 6.6 Conclusion. References. Chapter 7. SERS-based single molecule detection. 7.1 Discovery and development of single molecule SERS. 7.2 Verification of single molecule SERS. 7.3 Nanogap engineering and molecular localization at electromagnetic hot spot for single molecule SERS. 7.4 Designed substrate for single molecule SERS. 7.5 Application of single molecule SERS. 7.6 Conclusion. References. Chapter 8. Designed SERS probes for detection application with improved signal reproducibility. 8.1 Introduction. 8.2 Molecular Raman reporter coated plasmonic nanoparticle as SERS probe. 8.3 SERS-based detection via molecular analyte-mediated assembly of plasmonic nanoparticle. 8.4 SERS-based detection via molecular analyte-mediated plasmonic nanoparticle dimer formation. 8.5 SERS-based detection via engineering-based plasmonic hot spot generation. 8.6 Other engineering approaches for SERS-based detection. 8.7 Conclusion. References. Chapter 9. Chemical analysis by SERS. 9.1 Introduction. 9.2 Quantitative detection application. 9.3 Environmental monitoring. 9.4 SERS in forensic science. 9.5 Identification of catalytic intermediates. 9.6 Enantioselective discrimination of chiral molecules. 9.7 Conclusion. References. Chapter 10. Biomedical applications of SERS. 10.1 Introduction. 10.2 Bioassays. 10.3 Detection of pathogens. 10.4 Detection of cells and cellular biochemicals. 10.5 Bioimaging. 10.6 Conclusion. References. Chapter 11. Outlook and future of SERS. 11.1 Introduction. 11.2 Advancement in SERS substrate fabrication. 11.3 Challenges on quantitative SERS with high sensitivity. 11.4 Temporal and spatial resolution limits in SERS. 11.5 Coupling SERS with other platforms. 11.6 Machine learning and SERS. 11.7 Conclusion. References

About the author

Nikhil R. Jana is a Professor at the School of Materials Science, Indian Association for the Cultivation of Science, Kolkata, India. He received his undergraduate degree (1987) from Midnapore College and Masters (1989) and PhD degree (1994) from Indian Institute of Technology, Kharagpur. He has worked as a postdoctoral fellow at the University of South Carolina-USA (1999¿2001) and University of Arkansas-USA (2003) and Scientist at the Institute of Bioengineering and Nanotechnology-Singapore (2004-2008). His research group designs colloidal nanobioconjugate for controlling cellular processes, develops nanoprobes/nanodrugs for sub-cellular targeting/imaging and investigates colloidal nanodrugs for therapeutic applications. His group has published 220 peer-reviewed research articles in internationally recognized journals, which have about 30,000 citations. He has been serving as an Associate Editor of ACS Applied Nano Materials since 2019.

Product details

• Authors: Nikhil Ranjan Jana, Nikhil Ranjan (Indian Association for the Cu Jana
• Publisher: Taylor & Francis Ltd.
• Languages: English
• Product format: Hardback
• Released: 24.06.2025
• EAN: 9781032622897
• ISBN: 978-1-0-3262289-7
• No. of pages: 162
• Subjects: Natural sciences, medicine, IT, technology > Physics, astronomy > Electricity, magnetism, optics; SCIENCE / Spectroscopy & Spectrum Analysis, Electrical Engineering, Materials science, Optical physics, Spectrum analysis, spectrochemistry, mass spectrometry