Women and Health: Volume 1 - Volume 2

Women and Health, Third Edition, Volume Two provides a comprehensive overview of health issues affecting women at various stages of life, from adolescence to old age. Unlike other books that focus solely on reproductive health, this volume covers a broad spectrum of topics including osteoporosis, breast cancer, domestic violence, sexually transmitted diseases, occupational hazards, eating disorders, heart disease, chronic illnesses, substance abuse, and the impact of societal and behavioral factors on health. Its international perspective ensures a holistic approach to understanding women's health.

In this new edition, the book emphasizes the health of mid-life and older women, incorporating the latest scientific findings and controversies. It delves into genetics and the influence of sex and gender on health, offering valuable insights for lay readers, clinicians, and health research scientists. This edition captures the maturity of the field of women's health since previous editions, presenting an updated compendium of the epidemiology of health conditions affecting women throughout their lives.

List of contents

Section A Metalloenzymes
1. Introduction to metalloenzymes: From bench to bedside

Section B Magnesium and calcium-containing enzymes
2.1 DNA and RNA polymerases
2.2 Reverse transcriptase
2.3 Integrase
2.4 Cyclin-dependent kinase 2 (CDK2)
2.5 Catechol-O-methyltransferase (COMT)
2.6 D-Alanine-D-alanine ligase
2.7 Paraoxonases
2.8 Phospholipases A2

Section C Zinc enzymes
3.1 Carbonic anhydrases
3.2 Metallo-ß-lactamases
3.3 Bacterial zinc proteases
3.4 Matrix metalloproteases
3.5 A disintegrin and metalloproteinases (ADAMs) and tumor necrosis factor-alphaconverting enzyme (TACE)
3.6 Angiotensin-converting enzyme
3.7 Histidinol dehydrogenase
3.8 Histone deacetylases and other epigenetic targets
3.9 CD73 (5'-Ectonucleotidase)
3.10 Glyoxalase II
3.11 Glutamate carboxypeptidase II
3.12 Neutral endopeptidase (neprilysin)

Section D Other metalloenzymes
4.1 The role of arginase in human health and disease
4.2 Methionine aminopeptidases
4.3 1-Deoxy-D-xylulose 5-phosphate reductoisomerase, the first committed enzyme in the MEP terpenoid biosynthetic pathway- Its chemical mechanism and inhibition

Section E Nickel enzymes
5.1 Urease
5.2 Methyl-coenzyme M reductase

Section F Iron enzymes (heme-containing)
6.1 Cyclooxygenase
6.2 Cytochrome P450 (inhibitors for the metabolism of drugs)
6.3 Aromatase

Section G Iron enzymes, non-heme containing
7.1 Nonheme mono- and dioxygenases
7.2 Indoleamine 2,3-dioxygenase

Section H Copper enzymes
8.1 Superoxide dismutases inhibitors
8.2 Tyrosinase enzyme and its inhibitors: An update of the literature

Section I Cadmium enzymes CAs
9. CDCA1, a versatile member of the ¿-class of carbonic anhydrase family

Section J Molybdenum enzymes
10. Molybdenum enzymes

Section K Tungsten-containing enzymes
11. Tungsten-containing enzymes

About the author

Dr. Rebecca Troisi is a research epidemiologist with expertise and extensive experience in the areas of reproductive health, cancer, and life course epidemiology at the Division of Cancer Epidemiology and Genetics, National Cancer Institute. Dr. Troisi leads the Diethylstilbestrol Follow-up Study and has many domestic and international collaborations including the Nordic Project. As well as having co-edited the second edition of Women and Health, she has authored over 150 peer-reviewed publications, many as first or last author, and several book chapters. Her current position at the National Institute of Health includes collaboration with the Office of Research on Women’s Health providing an overview and big picture regarding current issues and initiatives in this area.Dr. Kathryn Rexrode is the Chief of the Division of Women’s Health in the Department of Medicine at Brigham and Women’s Hospital (BWH) and an Associate Professor of Medicine at Harvard Medical School. Dr. Rexrode is a general internist and has broad and deep research experience in women’s health, with a particular expertise in cardiovascular disease in women. She leads multiple grants from the National institute of Health and is the author of more than 250 research publications. Dr. Rexrode is a Fellow of the American Heart Association and Chair of the Women and Special Populations Committee.Dr. Yvette Cozier is an Associate Professor of Epidemiology, and the Associate Dean of Diversity, Equity, Inclusion and Justice (DEIJ) at Boston University School of Public Health. She is also a Senior Epidemiologist at the Slone Epidemiology Center at Boston University School of Medicine. A social epidemiologist, Dr. Cozier’s overall research focus has been on the influence of psychosocial and structural factors on health - including racism and neighborhood socioeconomic status (SES). Dr. Cozier co-leads (MPI) the Black Women’s Health Study (BWHS), a prospective follow-up of over 59,000 African American women begun in 1995. She has published over 100 abstracts, manuscripts, invited commentaries and reviews, monographs, and book chapters on health disparities, cardiometabolic, and immune-mediated conditions including obesity, lupus, and sarcoidosis.Dr. Goldman’s career spans more than thirty-five years and includes extensive experience in research design, methodology, and analysis. As Director of Clinical Research, she supervised faculty and resident research in reproductive endocrinology and infertility, maternal-fetal medicine, urogynecology, and gynecologic oncology. Dr. Goldman completed graduate and post-graduate study in epidemiology at Harvard University’s School of Public Health where she also served on the faculty for more than a decade. During the development of the first edition of Women & Health she received a Health Sciences Fellowship at the Radcliffe Institute for Advanced Study at Harvard University. Dr. Goldman is a Fellow of the American College of Epidemiology and a lifetime member of the American Society for Reproductive Medicine. She was previously an Associate Editor of the American Journal of Epidemiology, a chartered member of the NIH IRAP study section, and an Investigator in the Cancer Epidemiology and Chemoprevention Research program at Dartmouth’s Norris Cotton Cancer Center.

Product details

• Assisted by: Yvette Cozier (Editor), Goldman Marlene B. (Editor), Kathryn Rexrode (Editor), Troisi Rebecca (Editor)
• Publisher: Elsevier
• Languages: English
• Product format: Hardback
• Release: 27.03.2026
• EAN: 9780443215544
• ISBN: 978-0-443-21554-4
• Subjects: Natural sciences, medicine, IT, technology > Biology > General, dictionaries; SCIENCE / Life Sciences / General, HEALTH & FITNESS / Women's Health, SCIENCE / Life Sciences / Biology, Women’s health, Biology, life sciences, Life sciences: general issues, Clinical and internal medicine