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Fundamentals and Therapeutic Applications of Liposomes provides an in-depth exploration of liposomal delivery systems for therapeutic purposes. This comprehensive book covers the synthesis and scaling up of liposomes for clinical use, examining their diverse applications in cancer therapy, immunotherapy, gene delivery, wound healing, viral disease, and neurological disorders. It also summarizes the regulatory aspects associated with clinical translation and industrial production. The book addresses the toxicity, safety, and environmental considerations of using liposomes for therapeutics, making it a useful resource for researchers, academics, and R&D groups interested in the development, production, and application of liposomes in various therapeutic settings.
List of contents
1. History, introduction, and physicochemical properties and characterization parameters of liposomes
2. Synthesis methods for liposomes and their scaling up for practical production
3. Recent technologies for industrial production of the liposomes
4. Biofate and cellular interactions of liposomes
5. Liposomes mediated anticancer drug delivery approaches for treatment of lung cancer
6. Liposomes mediated anticancer drug delivery approaches for treatment of breast cancer
7. Liposomes mediated anticancer drug delivery approaches for treatment of brain tumor
8. Liposomes mediated anticancer drug delivery approaches for treatment of pancreatic cancer
9. Liposomes mediated anticancer drug delivery approaches for treatment of skin cancer
10. Liposomes mediated anticancer drug delivery approaches for treatment of prostate cancer
11. Liposomes mediated anticancer drug delivery approaches for treatment of ovarian cancer
12. Liposome mediated drug co-delivery approaches for treatment of cancer
13. Liposomes mediated photodynamic therapy
14. Recent advances in liposomes mediated gene delivery
15. Liposomes mediated immunotherapy
16. Liposomes mediated drug delivery approaches for antibacterial and wound healing applications
17. Liposomes mediated drug delivery approaches for treatment of COVID-19 and other viral diseases
18. Liposomes mediated drug delivery approaches for treatment of Alzheimer's and Parkinson's diseases
19. Coated/hybrid liposomes as advanced drug delivery and theranostics applications
20. Recent progress on liposomes as vaccine delivery systems
21. Regulatory aspects of liposome-based drug delivery systems
22. Biological toxicity, safety issues and environmental hazards associated with liposomes
23. Optimization and troubleshooting, limitations, future opportunities for improvement in liposomes drug delivery technologies
24. Clinical translation of liposomes into market: Challenges and opportunities
25. Conclusion and future prospective of liposomes
About the author
Dr. Prashant Kesharwani is assistant professor of Pharmaceutics at Department of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya, Sagar, Madhya Pradesh, India. He has more than 12 years of teaching, research, and industrial experience at international levels from various countries, including the United States, Malaysia, and India. An overarching goal of his current research is the development of nanoengineered drug delivery systems for various diseases. He has more than 350 international publications in well-reputed journals and more than 25 international books (Elsevier). He is a recipient of many research grants from various funding bodies. He is also the recipient of several internationally acclaimed awards, such as “USERN Laureate award”, most prestigious “SERB-Ramanujan Fellowship Award”. He actively participates in outreach and scientific dissemination for the service of the wider community. His Number of citations is = 26779; h-index = 85; i-10 index = 370 (According to google scholar on March 2025). He has more than 30 international publications published in very high impact factor journals (Progress in Polymer Sciences IF 32.063, Molecular Sciences IF 41.444, Progress in Material Sciences IF 48.580, Advanced Materials IF 29.4, Drug Resistance Update IF 22.841 and Material Todays IF 32.072). He has presented many invited talks and oral presentations at prestigious scientific peer-conferences, received international acclaims and awards for research contribution, supervised students/junior researchers and actively participated in outreach and scientific dissemination for the service of the wider community.
