High Bleeding Risk Patients in Interventional Cardiology

This book will cover all areas concerning the high bleeding risk and fragile patients (including CHIP). This milieu is becoming more and more common and requires specific attention and investment from the healthcare systems to be managed properly. The book will be divided into 4 macro-areas (coronary artery disease, valvular heart disease, peripheral arterial disease, high thrombotic risk patients), each of which include specific chapters on the latest technical advances, offering a thorough literature coverage as well. Additional sections are devoted to future diagnostic and therapeutic areas, depending on the disease and the patient's risk profile. Interventional cardiologists and cardiac surgeons dealing with PCI, coronary bypasses, left atrial appendage closure, aortic and mitral interventions in this patient subgroup will be provided with an overview of the latest techniques and innovative technologies in this area, that will help them improving the clinical outcome of their patients. The invited group of collaborators was selected from among the most experienced physicians in the world, from Asia, North and South America and Europe.

List of contents

Foreword.- Preface.- I- General concepts.- 1. The evolving phenotype of the patient undergoing interventional cardiology procedures.- 2. Prognostic Impact of Bleeding in Interventional Cardiology.- 3. From GUSTO to TIMI to BARC.- 4. The Conundrum between HBR and HTR.- II- Revascularization strategies in HBR patients.- 5. Percutaneous Coronary Intervention in the Elderly.- 6. Revascularisation Strategies in Frail Patients.- 7. Revascularization strategies in HBR patients: the selection of coronary stent.- 8. The DCB Philosophy.- 9. DCB: Clinical Data from Registries to Randomized Trials.- 10. Is there a potential advantage of DCB over DES, on the long term?.- 11. Protected PCI in High Bleeding Risk Patients.- 12. Contemporary Bypass Techniques in Hybrid Revascularization.- 13. Hybrid Coronary Revascularization.- III- Structural heart interventions in HBR patients.- 14. Left atrial appendage closure: from randomized trials to contemporary registries.- 15. Tips and tricks for a successful and safe LAAO procedure.- 16. Transradial balloon aortic valvuloplasty.- 17. Minimalistic TAVI setup in high bleeding risk patients.- IV- Antithrombotic therapy in HBR patients.- 18. Intravenous Antiplatelet Drugs.- 19. Parenteral Anticoagulant Therapy.- 20. DAPT after coronary stenting: for how long and which drug.- 21. De-escalation of DAPT.- 22. Single antiplatelet therapy after DCB angioplasty.- 23. Triple or double antithrombotic therapy in Atrial Fibrillation patients treated with stents.- 24. Management and Prognostic Implications of Bleeding Post-TAVI.- V- Management and prognostic implications of bleedings in HBR patients.- 25. High bleeding risk in complex high risk and indicated patient.- 26. Antithrombotic Therapy after Transcatheter Aortic Valve Implantation or Left Atrial Appendage Occlusion.

About the author

Bernardo Cortese is an interventional cardiologist, Interventional Director of the Coronary Center at Harrington Heart & Vascular Institute, University Hospitals Cleveland, full professor of Medicine at Case Western Reserve University, Cleveland, Director and President of DCB Academy, a scientific and educational Society, and  President of the Scientific Committee of Fondazione Ricerca e Innovazione Cardiovascolare, a research institution based in Milan. An expert in the areas of complex coronary interventions, coronary atherectomy, drug-coated balloons, bioresorbable scaffolds, antithrombotics, optical coherence tomography, and left main coronary revascularization, Dr Cortese has performed more than 5000 coronary and peripheral percutaneous interventions as first operator.  He is involved in several educational programs, including the “DEB School”, and he is author of more than 380 publications indexed in Pubmed. He published two books with Springer “Left Main Coronary Revascularizaion” and “Drug-Coated Balloons”.
Stefano Rigattieri is an interventional cardiologist working at Sant'Andrea University Hospital in Rome, Italy. His fields of clinical and research activity include complex coronary interventions, invasive coronary physiology and imaging, and structural interventions. His research activity has mainly focused on pharmaco-invasive management of acute coronary syndromes, transradial approach, radiation exposure in interventional cardiology and transcatheter aortic valve implantation. He has been co-investigator of several randomised trials, such as MATRIX, RIFLE-STEACS, DUBIUS and FIRE. He was a member of the National Board of the Italian Society of Interventional Cardiology (years 2017 to 2021) and of the European Association of Percutaneous Cardiovascular Interventions Quality Improvement Committee (years 2022 to 2024). He is author of more than 100 publications indexed in Pubmed.

Summary

This book will cover all areas concerning the high bleeding risk and fragile patients (including CHIP). This milieu is becoming more and more common and requires specific attention and investment from the healthcare systems to be managed properly. The book will be divided into 4 macro-areas (coronary artery disease, valvular heart disease, peripheral arterial disease, high thrombotic risk patients), each of which include specific chapters on the latest technical advances, offering a thorough literature coverage as well. Additional sections are devoted to future diagnostic and therapeutic areas, depending on the disease and the patient's risk profile. Interventional cardiologists and cardiac surgeons dealing with PCI, coronary bypasses, left atrial appendage closure, aortic and mitral interventions in this patient subgroup will be provided with an overview of the latest techniques and innovative technologies in this area, that will help them improving the clinical outcome of their patients. The invited group of collaborators was selected from among the most experienced physicians in the world, from Asia, North and South America and Europe.

Product details

• Assisted by: Bernardo Cortese (Editor), Rigattieri (Editor), Stefano Rigattieri (Editor)
• Publisher: Springer, Berlin
• Languages: English, German
• Product format: Hardback
• Release: 11.06.2025, delayed
• EAN: 9783031873010
• ISBN: 978-3-0-3187301-0
• No. of pages: 299
• Illustrations: XI, 299 p. 73 illus., 69 illus. in color.
• Subjects: Natural sciences, medicine, IT, technology > Medicine > General; Health Sciences, elderly patients, Tavi, High-risk percutaneous coronary intervention, Left atrial appendage occlusion, High Risk Percutaneous Coronary Intervention (CHIP)