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Informationen zum Autor Pascal Kintz Klappentext Written by well-known! international authors! this comprehensive reference provides practical coverage of the best hair drug testing techniques and examines the drugs themselves. The authors review all new developments! the validation of analytical procedures! and the interpretation of data. Some of the applications discussed include doping! drug-facilitated crime investigating! workplace testing! and the granting of drivers' licenses. The authors describe specific drugs! such as opiates! cocaine! and cannabis! and discuss the different testing methods of them. The book also covers postmortem toxicology! pitfalls created by passive exposure! and testing for metals! including inductively coupled plasma spectrometry (ICP-MS)! hair multielementary analysis! and the new speciation analysis. Zusammenfassung Offers coverage of some of the best hair drug testing techniques. This work reviews developments, the validation of analytical procedures, and the interpretation of data. It describes specific drugs, such as opiates, cocaine, and cannabis, and discuss the different testing methods of them. Inhaltsverzeichnis DRUG INCORPORATION INTO HAIRHair PhysiologyDrug Incorporation RoutesMechanisms of BindingGeneral DiscussionConcluding RemarksReferencesPASSIVE EXPOSURE! DECONTAMINATION PROCEDURES! CUTOFFS! AND BIAS: PITFALLS IN THE INTERPRETATION OF HAIR ANALYSIS RESULTS FOR COCAINE USEIntroduction Historical Concerns for Passive Exposure in Hair AnalysisMechanisms for Incorporation of Drugs into HairDrugs in the EnvironmentDecontamination ProceduresCutoffs and Why They MatterBias in Hair TestingConclusions AcknowledgmentsReferencesOPIOIDS TESTING IN HAIRIntroduction OpiatesConclusions ReferencesHAIR ANALYSIS FOR COCAINEIntroduction Analytical MethodologiesQuality ControlInterpretation of ResultsAcknowledgmentsAbbreviations ReferencesDETERMINATION OF CANNABINOIDS IN HUMAN HAIRIntroduction Metabolism! Incorporation of Cannabinoids into Hair Analytical Techniques for the Detection of Cannabinoids Decontamination ProcessesIssues to Be ConsideredCriteria for Obtaining a Cannabis-Positive Hair-Test ResultControlled Studies: Empirical Data Analysis of a Large Sample ofHair Specimens Reported Concentrations of Cannabinoids in Hair Conclusions ReferencesAMPHETAMINE DETERMINATION IN HAIRIntroduction PreambleAmphetamine DeterminationConclusionReferencesPHARMACEUTICALS IN HAIRIntroduction Discussion and ConclusionReferencesSCREENING STRATEGIES IN HAIR ANALYSIS ON DRUGSIntroduction Immunochemical Screening in Hair AnalysisScreening and Confirmation by GC-MS/MS Multianalyte Screening Using LC-MS/MSCrime Cases Solved by Screening Hair Using LC-MS/MS Conclusions ReferencesCLINICAL APPLICATIONS OF HAIR ANALYSISIntroduction Hair Analysis in Psychiatric PatientsHair Analysis in Epileptic ManagementHair Analysis as Evidence of Prenatal and Postnatal Exposure toDrugs and Tobacco Hair Nicotine as a Marker of Active and Passive Exposure to TobaccoDrug Addiction and Opiate-Maintenance Programs Therapeutic Drug MonitoringReferencesHAIR IN POSTMORTEM TOXICOLOGYIntroduction Methodological AspectsStrategies in Postmortem WorkConclusions and Take-Home Message ReferencesDETECTION OF DOPING AGENTS IN HUMAN HAIRIntroduction ProceduresDetection of Doping AgentsDiscussion Conclusions ReferencesAPPLICATIONS OF HAIR IN DRUG-FACILITATED CRIME EVIDENCE Introduction Analytical StrategyCase ReportsDiscussion ConclusionReferencesAPPLICATION OF HAIR IN DRIVING-LICENSE REGRANTINGIntroduction Sensitivity of Drug Abuse Detection: Comparison betweenUrine and Hair Analysis Hair Sampling for Drug AnalysisManipulation of Drug Concentrations in Hair Hair Analysis for Regranting Driver's LicenseRegulations in Other Countries Conclusions ReferencesALCOHOL MARKERS IN HAIRGeneral Problems in Detection of Chronic Alcohol Abuse Fatty Acid Ethyl Esters (FAEE)Ethylglucuronide (EtG)Combined Use of...
