Read more
Klappentext Bioactive-Based Nanotherapeutics explores the rapidly growing field of therapeutics. The book delves into bioactive nanotherapeutics and its enormous potential for revolutionizing disease treatment and management. In addition, the book presents a broad overview of the fundamentals of bioactive nanomaterials, their design strategies, and their therapeutic applications. Readers explore beneficial topics on the applications of bioactive nanotherapeutics for the treatment of various diseases, including cancer, GII, infectious diseases, and neurodegenerative disorders. Chapters explore various topics, including the basics of bioactive in bioactive nanotherapeutics, isolation methods of different bioactive compounds, and formulation development. It highlights recent advancements and the perspective of this approach for enhanced therapeutic outcomes. The chapters explore strategies for designing and engineering bioactive nanoparticles to achieve desired properties for specific therapeutic applications. It will be very useful for readers in their scientific studies, professional development, and design of new products containing natural activities. Inhaltsverzeichnis Preface xxxi 1 Basics of Nano-Bioactive Compounds and Their Therapeutic Potential 1 Jannat ul Firdaus, Sumitra Singh and Rakesh K. Sindhu 1.1 Introduction 2 1.2 Therapeutic Potential of Bioactive Compounds 3 1.3 Extraction Techniques for Obtaining Bioactive Compound 8 1.4 Novel Delivery Approach for Bioactive Compounds 9 1.5 Electrospinning 11 1.6 Micro- and Nanoencapsulation of Bioactive Compounds 11 1.7 Polymeric Nanoparticles (NPs) 12 1.8 Solid Lipid Nanoparticles 12 1.9 Nanoemulsions 12 1.10 Nanocrystals 13 1.11 Phytosomes 13 1.12 Therapeutic Potential of Nano-Bioactive Compounds 14 1.13 Conclusion 17 References 18 2 Recent Techniques for Isolation of Bioactive Components from Plants 27 Omonike O. Ogbole, Oluwagbenga V. Kayode, Feranmi J. Adelowokan and Oluwatoyin A. Odeku 2.1 Introduction 28 2.2 Extraction Methods 30 2.3 Recent Chromatographic Methods 35 2.4 Applications of Two-Dimensional Chromatographic Approaches 40 2.5 Hyphenated Techniques 40 2.6 Conclusion 43 References 43 3 Bioactive-Based Nanocarriers for Inflammatory Diseases 55 Jasdev Singh Tuteja, Supriya Shidhaye, Anamika Singh and Tamanna Narsinghani 3.1 Inflammation and Diseases 56 3.2 Nanocarriers as Drug Delivery System 58 3.3 Nanocarriers and Inflammation 59 3.4 Inflammation in Central Nervous System 60 3.5 Ophthalmological Inflammation 63 3.6 Cardiovascular Inflammation 65 3.7 Respiratory Inflammation 68 3.8 Inflammation in Gastric System 73 3.9 Excretory System Inflammation 77 3.10 Inflammation of the Reproductive System 81 3.11 Inflammation Associated with Dermatology 85 3.12 Muscular Inflammation 89 3.13 Skeletal Inflammation 92 3.14 Applications of Nanocarriers in Inflammation 96 3.15 Conclusion 101 References 102 4 Bioactive-Based Nanocarriers for Dermal Diseases 115 Nitika Garg, Sanchit Dhankhar, Samrat Chauhan and Suresh Beniwal 4.1 Introduction 116 4.2 Skin Anatomy and Physiology: Implications for Drug Delivery 117 4.3 Barrier Functions of the Skin 119 4.4 Transdermal Permeation Challenges 119 4.5 Factors Influencing Dermal Drug Penetration 120 4.6 Role of Nanocarriers in Enhancing Drug Penetration 122 4.7 Types of Bioactive-Based Nanocarriers 129 4.8 Design Principles and Fabrication Techniques 129 4.9 Characterization of Bioactive-Based Nanocarriers 130 4.10 Applications in Diverse Dermal Diseases 132 4.11 Precl...
