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This volume provides a concise yet comprehensive overview of minimal residual disease (MRD) testing. The text reviews the history of MRD testing, MRD testing for acute lymphoblastic leukemia/lymphoma, molecular diagnostics for MRD analysis in hematopoietic malignancies, the use of "difference from normal" flow cytometry in monitoring AML response, ML-DS for measurable residual disease detection, and advancements in next generation sequencing for detecting MRD.
Written by experts in the field, Minimal Residual Disease Testing: Current Innovations and Future Directions is a valuable resource for hematologists, oncologists, pathologists, and radiologists on the variety of technologies available to detect MRD and how best to integrate these platforms into clinical practice.
List of contents
Introduction.- Minimal Residual Disease Testing in Acute Lymphoblastic Leukemia/Lymphoma.- Molecular Diagnostics for Minimal Residual Disease Analysis in Hematopoietic Malignancies.- Monitoring AML Response Using "Difference From Normal" Flow Cytometry.- ML-DS: A Unique Condition for Measurable Residual Disease Detection.- Advancements in Next Generation Sequencing for Detecting Minimal Residual Disease.
About the author
Todd E. Druley, MD, PhDAssociate Professor of Pediatrics, Genetics and Developmental BiologyDirector, Fellowship Program in Pediatric Hematology and OncologyDirector, Pediatric Cancer Predisposition ProgramWashington University in St. LouisDepartment of Pediatrics
Division of Hematology and OncologyCenter for Genome Sciences and Systems BiologySt. Louis, MO USA
Summary
Provides a concise yet comprehensive overview on all aspects of minimal residual disease testing
Presented in an easy-to-read format
Written by experts in the field