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Biotechnology Engineering: A Practical Approach on Bioprocess Development from Lab to Industrial Scale comprehensively provides consolidated content related to biotechnology engineering that supports R&D to manufacture commercial products on an industrial scale to meet the market's requirements. The book's structured chapters, practical approach, and real-world case studies effectively fulfil knowledge and information needs in the bioprocessing and biotechnology field. The chapters cover a broad diversity of topics ranging from the basics of bioprocessing, scalable solutions, bioprocess optimization, collaboration opportunities with experts, and crucial information on regulatory compliance. As such the book bridges the gap between theory and real-world applications in the bioprocessing field. Biotechnology Engineering: A Practical Approach on Bioprocess Development from Lab to Industrial Scale serves as a desktop reference for academics, scientist, engineers and professionals working on bioprocess development, discussing bioprocess development with calculations and case studies, and highlighting modern bioreactors and software tools adopted in the bioprocess industry.
List of contents
PART A: Cell culture and Kinetic study1. Culturing of microbial, animal and plant cells in lab scale
2. Microbial growth and cell kinetics
3. Design, optimization, and Inoculum development for culturing the cells
4. Lab scale studies on Submerged Liquid Fermentation (SLF) and Solid State Fermentation (SSF)
PART B: Bioreactor handling and operation5. Fundamental of Bioreactors and accessories
6. Design Aspects and Aseptic Maintenance of Bioreactors
7. Cleaning Techniques for Bioreactors and Regulatory Standards
8. Bioreactor sterilization techniques and equipment
9. Standard Operating Procedures and Auditing in Bioprocess Industries
10. Operation and control of Submerged Liquid Fermenters
11. Operation and control of submerged solid fermenters
12. Equipment for downstream Product Recovery and Purification
13. Modern Reactors and Software Tools in Bioprocess Development
PART C: Bioreactor Scale up aspects and case studies14. Scale-Up Rules and Reactor Accessories
15. Scale-Up Strategies for Submerged Liquid Fermentation
16. Scale-Up Strategies for Solid State Fermentation
17. Scale-Up Constraints from Lab Scale to Industrial Scale
PART D: Bioproducts18. Commercial Bioproducts from Bioreactors
19. Bioproducts from Fermentation and their Economic Impact
20. Manufacturing Techniques for Bioproducts
