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This book illustrates the role of the human microbiome in health and diseases. It discusses the association of an imbalanced human microbiome with different human diseases, including inflammatory, metabolic conditions, neurological, cardiovascular, and respiratory diseases. The book further reviews the association between intestinal microbiota and immune defense systems. The book provides evolving knowledge of the development, complexity, and functionality of the healthy gut microbiota and covers interventions that modulate and stabilize the gut microbiota. Further, it introduces the human microbiome as a reservoir of AMR genes, the current knowledge on the resistome, and the recent and upcoming advances in molecular diagnostic approaches to unravel this reservoir. Toward the end, the book reviews the advances in understanding the human urinary microbiome and its potential role in urinary tract infection. The chapter also presents the dynamics of the skin microbiome and the association of microbiota with skin disorders and therapeutic interventions. This book is an invaluable read for health professionals, medical students, microbiologists, and scientific research communities who are eager to update themselves with recent trends in microbiome research.
List of contents
Chapter 1_A scoping review of research on the unfolding human microbiome landscape in the metagenomics era.- Chapter 2_Elucidating the Role of Gut-Brain-Axis in Neuropsychiatric and Neurological Disorders.- Chapter 3_Role of Gut Microbiome Composition in Shaping Host Immune System Development and Health.- Chapter 4_Understanding the probiotics and mechanism of immunomodulation interactions with the gut-related immune system.- Chapter 5_Antimicrobial agents induced microbiome dysbiosis and its impact on immune system and metabolic health.- Chapter 6_Nutritional Modulation of Gut Microbiota Alleviates metabolic and neurological disorders.- Chapter 7_Hepatocellular carcinoma and human gut microbiome: Association with disease and scope for therapeutic intervention.- Chapter 8_Influence of intestinal Microbiomes on the COVID progression and its effects by the immunotherapeutic modulation.- Chapter 9_The Human Breast Milk Microbiome: Establishment and resilience of microbiota over mother-infant relationship.- Chapter 10_The dynamics of skin microbiome: Association of microbiota with skin disorders and therapeutic interventions.- Chapter 11_Advances in human urinary microbiome: Functional role beyond infections.- Chapter 12_Role of microbiomes in defining the metabolic and regulatory networks that distinguishes between good health and a continuum of disease states.- Chapter 13_The microbiome- antibiotic resistome: Significant strategies towards Microbiome-Targeted therapeutic interventions in medicine.- Chapter 14_New paradigms on Microbiome diagnostics design and engineering.- Chapter 15_Microbiome Therapeutics-Emerging Concepts and Challenges in translational microbiome research.- Chapter 16_Insights on the new generation technologies and capabilities of bioinformatic tools to understand microbiome research and microbial world.
