Cell Cycle and Neuronal Death

Cell-Cycle Mechanisms and Neuronal Cell Death examines the role of cell cycle activation in the molecular mechanisms leading to neuronal degeneration. Leading Authors discuss this topic in relation to the major neurological disorders, including Alzheimer s disease, stroke and epilepsy. This book serves to gain new insights into the molecular determinants of neuronal death and to establish new targets for therapeutic intervention.

List of contents

Preface.- Cell Cycle Activation in Neurons: The Final Exit of Brain-Morpho-Dysregulation.- Paved with Good Intentions: The Link between Cell Cycle and Cell Death in the Mammalian Central Nervous System.- The Role of Presenilins in the Cell Cycle and Apoptosis.- Cell Cycle Activation and Cell Death in the Nervous System.- Cell Cycle and Chromosome Segregation: Defects in Alzheimer s Disease.- Alzheimer Disease: A New Beginning or a Final Exit?.- From Cell Cycle Activation to the Inhibition of the Wnt Pathway: A Hypothesis of How Neurons Die in Response to â-Amyloid.- Index.

Summary

Cell-Cycle Mechanisms and Neuronal Cell Death examines the role of cell cycle activation in the molecular mechanisms leading to neuronal degeneration. Leading Authors discuss this topic in relation to the major neurological disorders, including Alzheimer’s disease, stroke and epilepsy. This book serves to gain new insights into the molecular determinants of neuronal death and to establish new targets for therapeutic intervention.

Product details

• Authors: A. Copani, F. Nicoletti
• Assisted by: Agat Copani (Editor), Agata Copani (Editor), Nicoletti (Editor), Nicoletti (Editor), Ferdinando Nicoletti (Editor)
• Publisher: Springer Netherlands
• Languages: English
• Product format: Hardback
• Released: 01.01.2006
• EAN: 9780306478505
• ISBN: 978-0-306-47850-5
• No. of pages: 110
• Illustrations: 21 SW-Abb., 2 Farbabb., VII, 102 p.
• Series: Neuroscience Intelligence Unit; Neuroscience Intelligence Unit
• Subject: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine