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Informationen zum Autor John L. LaMattina, PhD , retired as president of Pfizer Global Research and Development in 2007 where he managed more than 13,000 scientists and support professionals in the United States, Europe, and Asia. Dr. LaMattina has received numerous awards including an Honorary Doctor of Science degree from the University of New Hampshire. Klappentext An insider's perspective on the pharmaceutical industryIt's easy to hate Big Pharma. After all, they charge a lot of money for life-saving drugs. You could argue that Big Pharma's incentive to generate income is antithetical to the needs of society. But, if you set costs aside, no reasonable person could argue against the industry's accomplishments. The pharmaceutical industry has cured many infectious diseases and some cancers, delayed the onset of heart disease, enabled AIDS patients to live long and productive lives, controlled the progression of arthritis, and reduced pain.Any thoughtful discussion on the pharmaceutical industry must be guided by the facts. Author John LaMattina, a thirty-year veteran and former president of Pfizer Global Research and Development, takes you through the realities and the myths surrounding the pharmaceutical industry, offering concrete illustrative examples. Rather than innuendo, he offers facts, answering your questions about the process and costs of pharmaceutical R&D in a compelling narrative focused on the discovery and development of new medicines.Divided into four parts, this book dispels common misconceptions, helping you arrive at your own informed conclusions:* Part One, A Matter of the Heart* Part Two, The Role of Pharmaceutical R&D in Healthcare* Part Three, The Profit Motive* Part Four, The FutureWith its emphasis on fact, John LaMattina's book is indispensable for anyone interested in understanding, advocating, or setting pharmaceutical policy, including general consumers, pharmaceutical executives, regulators, pharmaceutical researchers, and students."This is an important and timely book."-Dr. Richard A. Lerner, President of the Scripps Research Institute"Drug Truths is an authoritative, clear, and accessible exposition of the realities of drug discovery and development."-Professor E.J. Corey, Nobel Laureate, Harvard University Zusammenfassung This book answers the questions about the process and costs of pharmaceutical R & D in a compelling narrative focused on the discovery and development of important new medicines. Inhaltsverzeichnis ACKNOWLEDGMENTS ix INTRODUCTION xi PART I A MATTER OF THE HEART 1 CHAPTER 1 CHOLESTEROL DRUGS ARE UNNECESSARY 3 CHAPTER 2 INDUSTRY IS MORE INTERESTED IN "ME-TOO" DRUGS THAN IN INNOVATION 13 CHAPTER 3 IT TAKES INDUSTRY TOO LONG TO DISCOVER NEW DRUGS 23 PART II THE ROLE OF PHARMACEUTICAL R&D IN HEALTH CARE 39 CHAPTER 4 DRUGS ARE DISCOVERED BY ACADEMIA 41 CHAPTER 5 NEW MEDICINES ADD COSTS BUT LITTLE BENEFIT 50 CHAPTER 6 BIG PHARMA HAS FAILED AND SHOULD LEARN FROM BIOTECH SUCCESS 59 PART III THE PROFIT MOTIVE 69 CHAPTER 7 THE INDUSTRY INVENTS DISEASES 71 CHAPTER 8 NEW DRUGS ARE LESS SAFE THAN TRADITIONAL MEDICINES 79 CHAPTER 9 INDUSTRY SPENDS MORE ON ADVERTISING THAN ON R&D 91 CHAPTER 10 INDUSTRY DOES NOT CARE ABOUT DISEASES OF THE DEVELOPING WORLD 100 PART IV THE FUTURE 109 CHAPTER 11 BIG PHARMA'S DAY HAS PASSED 111 CHAPTER 12 FINAL REFLECTIONS 122 REFERENCES 124 INDEX 133 ...
