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Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat.
Detection, Diagnosis and Vaccine Development, the third volume of The Flaviviruses details the current status of technologies for detection and differentiation of these viruses, their use in surveillance and outbreak investigation, and also reviews the latest clinical research.
List of contents
Diagnosis and Surveillance
Serodiagnosis of Flaviviral Infections and Vaccinations in Humans
Molecular amplification assays for the detection of Flaviviruses
Virus Epidemiology, Ecology and Emergence
Japanese Encephalitis
Epidemiology of St Louis encephalitis virus
West Nile Virus: epidemiology and Ecology in North America
Dengue Epidemiology: Virus Epidemiology, Ecology and Emergence.
Epidemiology and Ecology of Yellow Fever virus
Virus Epidemiology, Ecology and Emergence of Tick-borne flaviviruses
Vaccines and Antiviral Agents
Formalin-inactivated whole virus and recombinant subunit flavivirus vaccines
Empirically derived live, attenuated vaccines against Dengue and Japanese Encephalitis
DNA vaccines for Flaviviruses
Chimeric Flaviviruses: novel vaccines against dengue fever, tick-borne encephalitis and Japanese encephalitis
Prospects for antiviral therapy
Report
"...the chapters are well written, and the editors have ensured continuity of a high standard of writing throughout the set...Given the wealth of information, with contributions by over 60 authors, The Flavaviruses, really is an essential series of books that belongs on every arbovirologists' bookshelf." --Stephen Higgs, Ph.D., University of Texas Medical Branch, U.S. (2004)
