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The volume has as primary focus multidimensional gas chromatography (heart-cutting systems, comprehensive 2D-GC systems and hybrid solutions) and its characteristic features for in depth investigation of complex fractions of odor-active volatiles. Contributions, from outstanding researchers in the field from Academia and industry, cover fundamentals aspects on the physiology of olfaction, the strategies to identify key-odorants from the bulk of detectable volatiles (sensomics), the principles of operation of multidimensional analytical platforms (i.e., comprehensive two-dimensional gas chromatography - GC×GC; heart-cut 2D-GC, hybrid systems), and the fundamental role of mass spectrometry in providing reliable and informative data. Insights on new systems design and configurations are also provided, including sample preparation and data processing strategies, as important steps of the whole analytical process. Real-world examples cover food volatiles, complex aroma mixtures, odors emitted from industrial plants, volatiles of interest in forensic and medical applications.
List of contents
Preface
Chiara Emilia Irma Cordero
1. Olfaction and the complex interaction between odourant ligands and their receptors
Franziska Haag and Dietmar Krautwurst
2. The sensomics approach: A useful tool to unravel the genuine aroma blueprint of foods and aroma changes during food processing
Michael Granvogl and Peter Schieberle
3. Heart-cutting and comprehensive multidimensional gas chromatography: Basic principles
Peter Q. Tranchida, Ivan Aloisi and Luigi Mondello
4. Multidimensional gas chromatography: Hyphenation with mass spectrometry
Peter Q. Tranchida, Barbara Giocastro and Luigi Mondello
5. Multidimensional gas chromatography platforms for the analysis of flavours and odorants
Michelle S.S. Amaral, Yada Nolvachai and Philip J. Marriott
6. Sample preparation strategies for comprehensive volatile fingerprinting
Flavio A. Franchina and Giorgia Purcaro
7. GC × GC data visualization, processing, and analysis
Stephen E. Reichenbach
8. Investigation of food flavours by multidimensional and comprehensive gas chromatography
Johannes Kiefl, Lara Joanna Schulze, Ingo Gebauer, Uwe Schaefer, Isabel Rommel, Thomas Heitefaut, Mona Frederike Hauke, Stephan Neumann, Birgit Kohlenberg and Petra Slabizki
9. Exploring food volatilome by advanced chromatographic fingerprinting based on comprehensive two-dimensional gas chromatographic patterns
Simone Squara, Federico Stilo, Marta Cialiè Rosso, Erica Liberto, Carlo Bicchi and Chiara Cordero
10. Volatile organic compounds and odourants analysis in industrial gas chromatography
Jim Luong and Ronda Gras
11. Use of GC × GC for the characterization of odours in forensic applications
Lena M. Dubois, Gwen O'Sullivan, Pierre-Hugues Stefanuto, Court D. Sandau and Jean-François Focant
12. The diagnostic purpose of odorant patterns for clinical applications using GC × GC
Marco Beccaria, Pierre-Hugues Stefanuto, Giorgia Purcaro and Flavio A. Franchina
About the author
Chiara Cordero (orcid.org/0000-0003-3201-0775) is Full Professor of Food Chemistry at the University of Turin (Italy); her research interests focus on: (a) development of innovative and advanced instrumental configurations for comprehensive two-dimensional gas chromatography (GC×GC) coupled to Mass Spectrometry (MS) for food-omics investigations (profiling and fingerprinting approaches); (b) discovery of food intake markers (food metabolomics, nutrimetabolomics and volatilomics) in bio-fluids after diet-induced derangements; (c) development and application of miniaturized, fully automated and solvent-free sample preparation approaches (Solid Phase Microextraction SPME, Stir Bar Sorptive Extraction SBSE) for sensomic characterization of food.
In 2008, Chiara was awarded with the "Leslie S. Ettre” Award for “original research in capillary gas chromatography with an emphasis on environmental and food safety" and in 2014 received the “John B. Phillips Award” for her research activity in the field of comprehensive two-dimensional gas chromatography. In 2016 Chiara was included by The Analytical Scientist in the “Women Power List” as one of the 50 most influencing women in the analytical sciences.
