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Fermented milks are sources of bioactive peptides that can modulate intestinal functions. Milk hydrolysates fermented with Lactobacillus paracasei, Enterococcus faecalis, Enterococcus faecium, Bifidobacterium longum, Lactobacillus plantarum and Streptococcus thermophillus were analyzed. Their action on the intestine of mice sensitized to beta-Lg and milk was followed by histology of the jejunum. The results showed that the strains had proteolytic performance and antioxidant capacity. The preventive effect showed a slight production of anti-Blg IgG and IgE in animals fed the hydrolysates. The ex-vivo study showed that the response to allergen stimulation was lower. Intestinal histological studies revealed, in some groups, minor damage with weaker inflammatory signs and more or less enlarged villi. We conclude that hydrolysates have a preventive and therapeutic effect, and appear to have a protective effect on intestinal epithelium. The L.paracasei strain is an interesting candidate, with marked therapeutic and preventive effects.
About the author
Dr Kawthar BELKAALOUL, Profesor e investigador, jefe del curso de Biología y Fisiología Animal, jefe de equipo: Propiedades de los probióticos e inmunomodulación de la función intestinal en la alergia a las proteínas de la leche de vaca. Facultad de Ciencias Naturales y de la Vida . Universidad ORAN1 Ahmed Ben Bella.
